Th1/Th2细胞因子网络失衡与毛细支气管炎  

Th1/Th2 Cytokine Network Imbalance and Bronchiolitis

作　　者：黄燕[1] 

机构地区：[1]大连市儿童医院呼吸内科,辽宁大连116012

出　　处：《医学综述》2008年第16期2427-2430,共4页Medical Recapitulate

摘　　要：毛细支气管炎是由病毒引起的婴幼儿最常见的急性下呼吸道炎症,但其临床表现及转归与一般感染性炎症不同,而是与哮喘有许多相似之处,且病后哮喘发生率高,国内外许多实验证据也显示其与哮喘有内在联系,如在哮喘发作期出现的许多细胞因子及炎性物质都能在毛支中找到,本文正是以Th1/Th2细胞因子网络为主要切入点,对近年有关毛细支气管炎的免疫学发病机制进行综述,并从这一角度揭示毛支与哮喘的内在联系。Bronchiolitis is the most common acute lower respiratory tract inflammation in infants resulting from virus. Its clinical manifestation and outcome are are different from the common infection while similar with asthma,Further more,the asthma also has high incidence after the suffering from this disease. Many do- mestic and foreign experimental evidence also indicated there were some inherent link between asthma and bronchiolitis. This paper reviews pathogenesy of bronchiolitis in immunology in order to disclose the inherent link between them based on the Th1/Th2 cytokines.

关 键 词：毛细支气管炎 呼吸道合胞病毒 细胞因子 

分 类 号：R562.11[医药卫生—呼吸系统]