针刺治疗脑梗死恢复期多中心随机对照研究——中医证候疗效评价的报告  

A Multicenter Randomized Controlled Trial of Acupuncture Treatment for the Convalescent Stage of Cerebral Infarction-Report on the Assessment of Therapeutic Effects on Syndrome in Traditional Chinese Medicine

作　　者：杨志新[1] 卞金玲[1] 许军峰[1] 申鹏飞[1] 熊杰[2] 郭家奎[3] 张智龙[4] 李军[1] 石学敏[1] 

机构地区：[1]天津中医药大学第一附属医院 [2]天津市武警医学院附属医院 [3]天津中医药大学第二附属医院 [4]天津市中医院

出　　处：《上海针灸杂志》2008年第8期3-6,共4页Shanghai Journal of Acupuncture and Moxibustion

基　　金：国家973项目(2006CB504504);天津市科技攻关重大科技项目(05YFGDSF02300)

摘　　要：目的探讨醒脑开窍针刺治疗脑梗死恢复期的临床疗效。方法多中心前瞻性随机对照临床研究。天津市600例脑梗死患者以病程分层随机,恢复期234例,以SAS编码,随机分配到醒脑开窍针刺组和传统针刺组(简称醒脑组和传统组)。醒脑组116例,接受醒脑开窍针刺(每日1次,共4星期)和常规治疗;传统组118例,接受传统针刺和常规治疗。随访6个月。中医证候疗效评价,①证类诊断、证型;②病类诊断及程度;③证候诊断及程度。结果两组患者基线资料相似(P>0.05);治疗期末两组在证类诊断、证型改变上比较差别无统计学意义,在病类诊断(u=2.64,P=0.008)及程度(u=-4.19,P=0.00)、证候诊断(u=0.70,P=0.48)及程度(χ2=5.53,P=0.06)改变上,醒脑组优于传统组。结论在中医证候疗效方面醒脑开窍针刺优于传统针刺。Objective To investigate the clinical efficacy of brain - activating and orifice - opening acupuncture in treating the convalescent stage of cerebral infarction. Methods A multicenter prospective randomized controlled trial was performed. Six hundred patients residing in Tianjing were randomly stratified according to disease duration. Two hundred and thirty-four patients in the convalescent stage were coded by SAS and randomly allocated to brain-activating and orifice-opening acupuncture （brain-activating） group and conventional acupuncture （conventional） group. The brain-activating group of 116 patients received brain -activating and orifice -opening acupuncture （once daily, for a total of 4 weeks） and routine treatment and the conventional group of 118 patients, conventional acupuncture and routine treatment. A follow - up of 6 months was performed. The indices for evaluating therapeutic effects ： The assessment of therapeutic effects on syndrome in traditional Chinese medicine （ TCM ） 1 ） Diagnosis and type of syndrome ; 2 ） Diagnosis and degree of disease ; 3 ） Diagnosis and degree of syndrome. Results Baseline data had no significant difference between the two groups of patients. There were no significant differences in diagnosis of syndrome and changes in type of syndrome between the two groups at the end of treatment. Changes in diagnosis （ u = 2.64, P = 0. 008 ） and degree （ u = - 4.19, P = 0.00） of disease and in diagnosis （u = 0.70, P = 0.48） and degree （X^2 = 5.53,P = 0.06） of syndrome were better in the brain-activating group than in the conventional group. Conclusion Brain-activating and orifice-opening acupuncture is superior to conventional acupuncture in the therapeutic effect on TCM syndrome.

关 键 词：脑梗死 针灸疗法 中医证候 结果评价 随机对照试验 多中心研究 

分 类 号：R246.6[医药卫生—针灸推拿学]