家兔豆状囊尾蚴病的组织病理学研究  

A Histopathologic Study on Cysticercus pisiformis Infected Rabbits

作　　者：孙晓林[1,2] 陈怀涛[2] 才学鹏[1] 

机构地区：[1]中国农业科学院兰州兽医研究所,家畜疫病病原生物学国家重点实验室/甘肃省动物寄生虫病重点实验室,兰州730046 [2]甘肃农业大学动物医学院,兰州730070

出　　处：《畜牧兽医学报》2008年第8期1100-1106,共7页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：国家“十一五”高科技研究发展计划(863)项目(2006ACOA207)

摘　　要：为研究家兔豆状囊尾蚴病的病理学变化，从33只自然感染病例采取肝脏、心脏、肾脏与肺脏组织块，经甲醛固定，梯度乙醇脱水，石蜡切片，切片厚度5～6μm，HE染色，光镜观察。结果表明，肝脏发生由豆状带绦虫六钩蚴穿行所致的出血坏死区以及在此基础上形成的上皮细胞、巨细胞肉芽肿。这种特异性病变可作为该病病理诊断的重要指征之一。同时也发现间质性肝炎、肾炎、肺炎及心肌纤维萎缩等变化。本研究为阐明该病的肝脏特征性病理变化及进一步探讨其发生机制奠定了基础。In order to observe the histopathological changes of the rabbits infected with Cysticer cus pisiformis, tissues of livers, hearts, kidneys and lungs from 33 naturally infected rabbits were collected. All the samples were fixed in the formalin and dehydrated with gradient alcohol. The 5-6 μm paraffin sections were made and stained with haematoxyylin and eosin, then were observed by light microscope. The results showed that zones of hemorrhaged necrosis caused by the migration of oncospheres of Taenia Pisiformis was formed on the surface of the rabbits liv- ers, as well as a granulation tumor consisted of epithelioid cell and multiple nuclear giant cell. This special pathological change could be one of the important diagnosis points of the disease. Meanwhile, other pathological changes such as interstitial hepatitis, brightism, pneumonia and heart muscle fiber atrophy were also observed. This study layed the foundation for the elucidation of the characteristic pathological change of liver and the development mechanism of this disease.

关 键 词：家兔 豆状囊尾蚴 组织病理学 肉芽肿 

分 类 号：S858.291[农业科学—临床兽医学]