一种新型可生物降解聚酯弹性体的制备及性能  

Preparation of a novel biodegradable polyester elastomer and its properties

作　　者：刘全勇[1,2] 谭天伟[2] 翁靖一[1] 田伟[3] 张立群[1] 

机构地区：[1]北京化工大学北京市新型高分子材料制备与成型加工重点实验室,北京100029 [2]北京化工大学北京市生物加工过程重点实验室,北京100029 [3]北京大学第四临床医学院,北京积水潭医院,北京100035

出　　处：《现代化工》2008年第8期49-52,54,共5页Modern Chemical Industry

基　　金：北京市自然科学基金(2061002)资助

摘　　要：制备了一种新型的、可生物降解聚(癸二酸-甘油-柠檬酸)酯弹性体(PGSC),并对其结构、组成、力学性能、热性能、生物降解性能进行了表征。PGSC弹性体的组成和性能,可以通过控制后期的热交联时间进行调节;而结构中存在的氢键作用,则大大影响了材料的热性能和生物降解性能。该弹性体期望被用作术后防粘连膜、诱导组织再生膜、药物缓释载体等方面。A novel biodegradable poly （sebacate-glycerol-citrate）（PGSC） elastomer is prepared, and its structure, composition, performances such as mechanical properties, thermal-properties and biodegradability are characterized. The composition and properties of prepared PGSC elastomer can be adjusted by controlling the thermal-curing time. Hydrogen bonding action exists in the materials, which greatly influences the thermal-properties and biodegradability. It is expected that PGSC elastomers can be used as anti-conglutination films in surgery, guided tissue regeneration membranes and drug delivery matrixes.

关 键 词：弹性体 聚酯 生物降解 制备 

分 类 号：TQ334.1[化学工程—橡胶工业]