年龄、心率与左室充盈参数的相关性分析  

Relational Analysis of Age and Heart Rate with the Measurements of Left Ventricular Filling by Doppler Echocardiography

作　　者：张化冬[1] 于东明[1] 李继红[1] 

机构地区：[1]首都医科大学附属北京天坛医院心内科

出　　处：《首都医科大学学报》1997年第4期333-336,共4页Journal of Capital Medical University

摘　　要：用多普勒超声心动图对７４例正常人的左室二尖瓣舒张期血流进行测定，并将此参数与心率、年龄进行多元线性回归分析，以确定年龄、心率对左室充盈参数的影响。结果：房缩期血流峰值（Ａ峰）及舒张早期血流峰值（Ｅ峰）、Ｅ／Ａ比值与心率、年龄相关密切（Ｒ＝０．６６，０．６５，Ｐ＜０．００１）。年龄每增加１０岁，Ａ值增加５．９（９５％ＣＩ５．０～６．８），Ｅ／Ａ减少０．２１（９５％ＣＩ０．１８～０．２４），心率每增加５次／ｍｉｎ，Ａ值增加２．３３（１．８０～２．８５），Ｅ／Ａ减少０．０６（０．０３～０．０９）。根据回归方程及９５％容许区间，制定心率、年龄左室充盈参数预测表，通过校正心率、年龄对左室充盈参数的影响，可以正确估价左室舒张功能的变化。74 subjects, aged 14～76 years, with heart rate range 55～104 bpm with no evidence of cardiovascular disease were included in this study. To determine the normal range of pulsed Doppler measurements of left ventricular filling,multiple regression was used to analyse the effects of age and heart rate on the measurements. The regression equation was used to calculate the predicted normal values adjusted by age and heart rate within 95% confidence interval (95% CI ),and the age, heart ratepredicted value table was made. The peak atrial filling velocity (A) and peak early filling velocity/peak atrial filling velocity (E/A) were significantly correlated with heart rate and age (R=0.66,0.65 P<0.001) .With every 10 years increase in age, an increase in 5.9 (95% CI 5.0～6.8 )cm/s, E/A decrease in 0.21(0.18～0.24),and with every 5 beats increase in heart rate,an increase in 2.33 ( 1.80～2.85 )cm/s,and E/A decrease in 0.06 ( 0.03～0.09 ) were found. With predicted values, changes of diastolic function could be assessed.

关 键 词：超声心动图 左室舒张功能 年龄 心率 

分 类 号：R540.45[医药卫生—心血管疾病]