外科围手术期抗菌药物应用研究  

Antibiotics Use During Perioperative Period in Surgery:Case-control Study

作　　者：肖秀红[1] 徐凤琴[1] 陈丽容[1] 张丽崧[1] 邵怀好[1] 

机构地区：[1]中山大学附属第二医院医院感染管理办公室,广东广州510120

出　　处：《中华医院感染学杂志》2008年第8期1143-1144,1154,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解外科围手术期抗菌药物应用情况。方法对2005年3月462例手术患者和2006年3月483例手术患者抗菌药物使用情况进行比较调查。结果2005、2006年组围手术期预防性应用抗菌药物使用率分别为99.48%、88.12%(P<0.05),2006年组手术前期、后期抗菌药物使用率下降(P<0.05),手术期使用率提高(P<0.05),术后预防用药时间缩短(P<0.05);2006年组应用二联、三联抗菌药物者比2005年组减少。结论依据《抗菌药物临床应用指导原则》加强管理行之有效,但仍有不足之处需加强管理。OBJECTIVE To investigate the antibiotic use during perioperative period in surgery aider administration according to Antibiotic Drug Use Guideline. METHODS The antibiotics usage status among 462 outpatient cases in Mar 2005 and 483 cases in Mar 2006 during perioperative period in surgery were surveyed. RESULTS The preventive use rate of antibiotic medication in surgery in 2005 and 2006 were respectively 99.48% and 88.12% （P〈0.05）; in comparison with that in 2005 group the percentage of preoperative and postoperative antibiotic medication in 2006 group was lower （P〈0. 05）; the percentage of intraoperative medication was higher （P〈0.05） ; the duration of postoperative medication was shorter（P〈0.05） and the percentage of 2, 3 or 4 kinds of antibiotics combined treatment was lower（P〈0.05）. CONCLUSIONS The administration of antibiotics usage during perioperative period has been proven effective, but there are some problems needed to be managed further.

关 键 词：围手术期 抗菌药物 预防 管理 

分 类 号：R378.1[医药卫生—病原生物学]