疏血通注射液治疗急性脑梗死的疗效和安全性研究  

Study on efficacy and safety of Shuxuetong injection in treatment of acute cerebral infarction

作　　者：黄海波[1] 王汉旻[1] 陈晓丽[1] 张征[1] 金得辛[1] 

机构地区：[1]温州医学院附属第一医院神经内科,浙江温州325000

出　　处：《中国医院药学杂志》2008年第15期1284-1286,共3页Chinese Journal of Hospital Pharmacy

摘　　要：目的:研究疏血通注射液治疗急性脑梗死的疗效和安全性。方法:将117例起病1周内急性脑梗死患者随机分为疏血通治疗组和维脑路通对照组,2组在常规抗血小板治疗的基础上均连续用药14d。观察治疗前后神经功能缺损评分、MRS评分、Barthel指数及血液凝血指标的变化。结果:治疗组患者神经功能缺损评分及MRS评分明显下降,Barthel指数上升而且血液凝血指标有明显改善。结论:疏血通注射液治疗急性脑梗死安全有效。OBJECTIVE To observe the efficacy and safety of Shuxuetong injection in treating patients with acute cerebral infarction. METHODS The 117 cases of patients with acute cerebral infarction were randomly divided into two groups： the control group was treated with Venoruton injection ,while the treatment group was infused with Shuxuetong injection. The two groups were continuously treated for 14 d. The changes of Neurological functional deficit scores, MRS scores, Barthel index （BI）, APTT, PT, and Fbg were observed between two groups before and after treatment. RESULTS Compared with the control group , the neurological function deficit scores and MRS scores were decreased, Barthel index （B I） were increased,and the levels of hemorheology indexes were ameliorated significantly in the Shuxuetong injection group. CONCLUSION Shuxuetong injection is effective and safe in the treatment of acute cerebral infarction.

关 键 词：疏血通 脑梗死 安全性 

分 类 号：R969[医药卫生—药理学]