清喉咽颗粒质量标准研究  

Study on the Quality Standard for Qinghouyan Granule

作　　者：邬梅 黄杨[1] 

机构地区：[1]怀化市药品检验所,湖南怀化418000

出　　处：《中医药导报》2008年第8期110-111,共2页Guiding Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:建立清喉咽颗粒的质量标准。方法:采用RP-HPLC法对处方中梓醇进行含量测定。色谱柱为Dikma C1(8 5μm,250 mm×4.6 mm);流动相为乙腈-0.08%磷酸(0.8∶99.2);检测波长为210 nm;柱温:25℃,流速:1.0 mL.min-1。结果:梓醇进样量在0.5110-2.555μg范围内与峰面积线性关系良好,r=0.9993.平均回收率为98.8%,RSD%=1.2%(n=6)。结论:该方法简便,结果准确,重现性好,可作为清喉咽颗粒的质量控制方法。Objective： To establish quality standard of Qinghouyan Granule. Methods： Using RP-HPLC for determination of catalposide, the chromatography consisted of the chromato bar of Dikma C18 （51μm, 250 mm×4.6 mm） with methanol-0.08% Phosphoric acid（0.8：99.2） as mobile phase at 210 nm of detection wavelength; The column temperature was 25℃, the flow rate was 1.0 mL·min^-1, Results： The linear ranges of catalposide were 0.5110-2.5550μg （r=0.9993）, The average recovery was 98.8%, and RSD% were 1.2%. Conclusion： These methods can be used for quality control of Qinghouyan Granule.

关 键 词：清喉咽颗粒 高效液相色谱法 梓醇 含量测定 

分 类 号：R927.2[医药卫生—药学]