The first total synthesis of ligudentatin A  

作　　者：Chen Xi Zhang Fu Qiang Bi Yu Lin Li 

机构地区：[1]State Key Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000, China

出　　处：《Chinese Chemical Letters》2008年第7期805-806,共2页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China (No.20272012);the Special Research Grant for Doctoral Sites in Chinese Universities (No.20010730001).

摘　　要：Ligudentatin A 1, a new phenolic norsesquiterpenes, was first synthesized starting from （＋）-perillaldehyde 3 through five steps, successively, in an overall yield of 20.8%. The key steps were the Diels-Alder reaction and aromatization of enone to phenol.Ligudentatin A 1, a new phenolic norsesquiterpenes, was first synthesized starting from （＋）-perillaldehyde 3 through five steps, successively, in an overall yield of 20.8%. The key steps were the Diels-Alder reaction and aromatization of enone to phenol.

关 键 词：Ligudentatin A （＋）-PeriUaldehyde Diels-Alder reaction AROMATIZATION 

分 类 号：O629[理学—有机化学]