阿霉素在纳米钴/碳纳米管/ITO修饰电极上的电化学行为  

Electrochemical Behaviour of the Adriamycin on Cobalt Nanoparticles/Multi-Walled Carbon Nanotubes/ITO Modified Electrode

作　　者：龚兰新[1] 魏翠梅[2] 胡劲波[2] 李启隆[2] 

机构地区：[1]新疆师范大学生命科学与化学学院,乌鲁木齐830054 [2]北京师范大学化学学院,北京100875 Xinjiang Normal Univ, Sch Life Sci & Chem, Urumqi 830054, Peoples R China; Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China

出　　处：《分析化学》2008年第8期1121-1124,共4页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金(No.20275007)资助项目

摘　　要：以固定在氧化铟锡(ITO)电极上的多壁碳纳米管为基底吸附纳米钴,制备了复合纳米材料修饰的电极(Co/CNT/ITO)。采用扫描电子显微镜(SEM)和电子能谱(EDS)等对其进行了表征。用纳米钴/碳纳米管/ITO电极,研究了阿霉素(ADM)的电化学行为。实验表明,该体系具有吸附性的不可逆过程,峰电位为-0.65V(vs.Ag/AgCl),峰电流与ADM浓度在1.0×10-9～5.0×10-7mol/L范围内呈线性关系;检出限为1.0×10-9mol/L。本法灵敏、简便。A multi-walled carbon nanotubes （MWCNTs）, and cobalt nanoparticles （CNPs） modified indium tin oxide （ITO） electrode （Co/CNT/ITO） was fabricated for the first time on an ITO electrode. The modified ITO electrode was characterized using cyclic vohammetry, scanning electron microscopy （SEM） and energy dispersive spectroscopy （EDS）. The electrochemical behavior of adriamycin （ADM） was studied by cyclic vohammetry at Co/CNT/ITO electrode. A sensitive reduction peak of adriamycin was obtained, The system belongs to the irreversible process with adsorptive characteristics, the peak potential was - 0. 65 V （ vs. Ag/AgC1）, the peak current was proportional to the concentration of adriamycin over the range of 1.0 ×10^-9 - 5.0 × 10^-7 mol/L and the detection limit is 1.0 × 10^-9mol,/L. The method was sensitive and convenient.

关 键 词：多壁碳纳米管 纳米钴 阿霉素 电化学行为 

分 类 号：O646.54[理学—物理化学] TB383[理学—化学]