中西医结合治疗卵巢功能低下性不育症48例临床观察  

Effect of integrative medicine treatment on 48 infertile patients with diminished ovarian reserve

作　　者：潘芳 俞瑾 

机构地区：[1]上海泰坤堂中医医院,上海200023 [2]上海坤泰女性健康中心,上海200031

出　　处：《生殖医学杂志》2008年第4期246-249,共4页Journal of Reproductive Medicine

摘　　要：目的观察中西医结合治疗卵巢功能低下性不育的疗效。方法对2004年5月至2006年12月诊治的48例卵巢功能低下不育患者,分为体外受精-胚胎移殖失败组16例、卵巢早衰组9例和卵巢功能低下组23例。从生命网络调控的观点出发,进行中药俞氏促卵泡方为主,辅以适量雌激素、中药外敷和身心健康指导半年以上的治疗。观察治疗后全身症状、基础体温(BBT)、排卵率、妊娠率以及"月经"第3天血清性激素变化。结果48例患者治疗后,全身症状明显改善,妊娠率40%,排卵率由治疗前的17%(8/48)增至治疗后的56%(27/48)(P<0.01)。治疗后各组患者血清雌二醇(E2)水平无明显变化(P>0.05),血清卵泡刺激素(FSH)水平及FSH/黄体生成素(LH)比值明显下降(P<0.05)。结论以俞氏卵泡方为主的中西医结合治疗,有效缓解卵巢功能低下患者的临床症状,提高排卵率和妊娠率。Objectives： To observe the effect of integrative medicine treatment on infertile patients with diminished ovarian reserve.Methods： Forty-eight infertile patients of diminished ovarian reserve were treated with integrative medicine from May 2004 to December 2006 in our center.Patients were divided into 3 groups： 16 patients with IVF-ET failure（IVF-ET group）,9 patients with premature ovarian failure（POF group） and 23 patients with diminished ovarian reserve（OV↓ group）.Yu＇s follicle replenishing recipe was administered daily for all patients,combined with different dosages of estrogen and mental-physical instructions.Symptoms,basic body temperature（BBT）,ovulation rate,pregnancy rate and serum sex hormones levels on cycle day 3 were observed before and after the treatment.Results： During the treatment,symptoms were gratefully relieved in all 48 patients,and the pregnancy rate was 40%.Ovulation rate was significantly increased from 17%（8/48） before treatment to 56 %（27/48） after treatment（P〈0.01）.Levels of serum E2 changed little（P〉0.05）,but serum FSH and FSH/LH reduced significantly（P〈0.05）. Conclusions： The main medicine—Yu＇s follicle replenishing recipe in the integrative medicine treatment not only increases ovulation rate and pregnancy rate in infertile patients with diminished ovarian reserve,but also helps them to relieve the symptoms.

关 键 词：中西医结合治疗 卵巢功能低下 不育症 生命网络调控 俞氏促卵泡方 

分 类 号：R711.75[医药卫生—妇产科学]