一起小学生甲3型流感暴发调查  

Survey of an outbreak of influenza A3 virus infection in primary school pupils

作　　者：贺征[1] 龚玉姣[1] 陈建东[1] 

机构地区：[1]广州市疾病预防控制中心,广东广州510080

出　　处：《中国热带医学》2008年第9期1623-1625,共3页China Tropical Medicine

摘　　要：目的分析一起小学甲3型流感暴发的特点和原因,为制定流感预防控制措施提供依据。方法按2005年广东省卫生厅《广东省流感样病例暴发疫情报告及调查处理工作指引(试行)》进行。结果本起暴发历时26d,罹患率为8.58%(70/816),7例为实验室确诊病例,余为临床诊断病例;男女发病差别没有统计学意义(P>0.05),病例无班级聚集性,有家庭聚集性。罹患率最高的是二年级16.00%(24/150),是否使用电脑室的不同人群罹患率差别有统计学意义(P<0.05);临床表现以急起发热(≥38℃),多伴有咳嗽(90%)、咽痛(42.86%)、头晕(35.71%)、流鼻涕(34.29%)、打喷嚏(34.29%)、头痛(21.43%)、腹泻(17.14%)等表现;采集10份病人咽拭子检测,流感抗原血凝素、病毒分离有7份结果均阳性,并鉴定为H3N2型流感病毒。经回顾性队列研究,使用电脑室人群和不使用电脑室人群流感感染率比较,RR值2.37(P<0.05),RR95%CI为1.36～4.11。结论未及时隔离发病学生、流感疫苗接种率低和电脑室共同暴露是造成DJ小学甲3型流感暴发的原因。Objective To describe the causes and characteristic of this outbreak of influenza A3, and provide scientific measure of preventing and controlling the reoccurring of epidemic situation. Methods All the programs are executed according to the guidelines and epidemic situation reports of influenza outbreak in Guangdong province （for trial implementation） of Guangdong provincial health department of Guangdong province in 2005. Results This epidemic situation lasted 26 days. The incidence rate of influenza was 8.58% （70/816）. There were 7 Lab - confirmed cases and the others are clinical diagnosed cases. There was no significant difference between boys and girls （P 〉 0.05）. The incidence rate showed obvious correlation with classes but had obvious correlation with families. The highest incidence rate was 16.00% （24/150） among students in grade 2. The difference of incidence rate between students who used Computer Classroom and who not used is significant in statistics （P 〉 0.05 ）. The main clinical manifestations were, high fever（ I〉 38℃ ）, accompanied with cough（ 90. 00% ）, dizziness（35.71% ）, nose running（34.29% ）, sneezing（34.29% ）, headache（21.43% ）, diarrbea（17.14% ） and so on. 10 cases are analysis from throat swabs, HA of influenza disease virus antigen and virus isolation of 4 students were positive. Students who used Computer Classroom compare with who not used is significant in statistics, RR is 2.37 （P 〈 0. 05）, RR95% CI is 1.36 - 4.1, Conclusion The outbreak tue to outbreak of influenza 3.3.

关 键 词：流感 爆发 分析 

分 类 号：R511.7[医药卫生—内科学]