子宫内膜接受性的建立和分子调控  

The Establishment and Molecular Regulation of Uterine Receptivity

作　　者：田振[1] 杨增明[1] 

机构地区：[1]东北农业大学生命科学学院,哈尔滨150030

出　　处：《动物学杂志》2008年第4期133-139,共7页Chinese Journal of Zoology

基　　金：国家自然科学基金项目(No.30570198)

摘　　要：胚泡着床是一个复杂的生理过程,依赖于胚泡发育和子宫内膜获得接受能力的同步进行。着床只发生在具有接受性的子宫内膜,而子宫内膜只在很短的时间内具有接受性,被称为"着床窗口"。子宫内膜接受性的建立涉及子宫腔上皮的形态学改变,以及甾类激素和许多细胞因子复杂的调控作用。本文综述了子宫内膜接受性的建立及其分子调控。Embryo implantation is a complex physiological process, depending on synchronized embryo development to the blastocyst stage and differentiation of uterus into the receptive stage. Embryo can only implant in receptive endometrium,whereas uterine receptivity is only present in a limited period during pregnancy,known as ＂implantation window＂ .The establishment of uterine receptivity involves morphological changes of luminal epithelium, as well as complicated regulation by steroid hormones and various cytokines.This review highlights the establishment of uterine receptivity and its molecular regulation.

关 键 词：子宫内膜接受性 胚泡 妊娠 

分 类 号：Q492[生物学—生理学]