儿童阻塞性睡眠呼吸暂停低通气综合症相关致病因素分析  

Etiological factor analysis of obstructive sleep apnea hypo-ventilation syndrome in children

作　　者：徐国刚[1] 吴立新[1] 武宇宏[1] 尚小领[1] 林彦涛[1] 

机构地区：[1]北方学院附属第一医院耳鼻咽喉-头颈外科,河北张家口075000

出　　处：《第四军医大学学报》2008年第16期1512-1514,共3页Journal of the Fourth Military Medical University

摘　　要：目的:观察分析儿童阻塞性睡眠呼吸暂停低通气综合征(OSAHS)相关的致病因素.方法:对我科收治的OS-AHS患儿196例进行回顾分析,并结合正常儿童调查情况,分析OSAHS相关的致病因素.结果:OSAHS患儿中有85.20%(167/196)扁桃体肥大,17.34%(34/196)体质量指数超过正常,91.84%(180/196)患儿腺样体与鼻咽部口径的比值(AN)大于正常,且OSAHS患儿的扁桃体肥大、腺样体与鼻咽部口径的比值与正常儿童比较差异有统计学意义(P<0.01),而体质量指数与正常儿童比较差异无统计学意义(P>0.05).结论:OSAHS患儿的发病与扁桃体肥大、腺样体与鼻咽部口径的比值存在密切的相关性,而与体质量指数没有密切相关性.AIM： To investigate the etiological factors of obstructive sleep apnea hypo-ventilation syndrome （OSAHS）. METHODS： 196 OSAHS children were retrospectively analyzed and compared with 200 normal children to find out the etiological factors of OSAHS. RESULTS： 85.20% OSAHS children （ 167/ 196） had tonsiUar hypertrophy （ P 〈 0. 01 vs normal control group）, and 91.84% （180/196） larger adenoidal nasopharyngeal （AN） ratio than the normal, with significant difference with the normal controls（P 〈0.01 ）. 17.34% （34/196） presented obesity, but it was not significantly different with normal children （ P 〉 0. 05）. CONCLUSION： The pathogenesis of OSAHS in children is related with tonsillar hypertrophy and larger AN ratio, but not with body mass index.

关 键 词：睡眠呼吸暂停 阻塞性/病因学 儿童 

分 类 号：R725.6[医药卫生—儿科]