紫外线吸收剂奥克立林的合成新工艺研究  

Study on New Process of UV Absorber Octocrylene

作　　者：翁赟[1] 许响生[1] 项斌[1] 朱颜[1] 

机构地区：[1]浙江工业大学精细化工研究所,浙江杭州310014

出　　处：《浙江化工》2008年第8期6-7,18,共3页Zhejiang Chemical Industry

摘　　要：在对甲苯磺酸催化下,氰基乙酸与异辛醇进行酯化反应;酯化液在-10℃冷却过滤,滤液中再加入二苯甲酮和催化剂乙酸铵,发生Knoevenagel缩合反应;后处理得到深色产物,经硅胶层过滤脱色后制得浅黄色的奥克立林纯品,总收率达86%(以实际消耗的异辛醇计),纯度为99%。Cyanoacetic acid and isooctanol were esterified, using p-toluenesulfonic acid as calalyst reactant was cooled at -10℃ and filtered, Benzophenone was added to occur Knoevenagel reaction catalysed by ammonium acetate. Yellow product was obtained after water-washing and distilling. Pale yellow octocrylene was gained after filtering by silica gel layer. The yield and purity were 86%and 99% respectively （on the basis of reacted isooctanol）.

关 键 词：奥克立林 2-氰基-3 3-二苯基丙烯酸-2’-乙基己酯 KNOEVENAGEL 合成 

分 类 号：TQ245.24[化学工程—有机化工]