心肌梗死与能量代谢  

Myocardial Infarction and Energy Metabolism

作　　者：李望[1] 魏英杰[1] 胡盛寿[1] 

机构地区：[1]中国医学科学院心血管病研究所,北京协和医学院,阜外心血管病医院,卫生部心血管疾病再生医学重点实验室,北京市100037

出　　处：《中国分子心脏病学杂志》2008年第4期246-248,共3页Molecular Cardiology of China

基　　金：国家"863"计划资助项目(2006AA02Z4B8)

摘　　要：心脏维持正常的功能需要正常的能量代谢。心肌梗死是引起心力衰竭的最常见的原因之一。心肌能量代谢的变化是心肌梗死及心力衰竭的病程发展中的一个重要的影响因素。能量代谢治疗为心肌梗死和心力衰竭的心肌保护及改善预后提供了新的治疗途径,对其临床和基础深入的研究具有重要的意义。本文就其目前的研究和进展作一综述。Myocardial infarction is one of the most common cause of heart failure. Myocardial infarction is associated with extensive remodeling which in due course will affect function and ultimately contribute to the transition from compensatory hypertrophy to cardiac failure. It is important to maintain normal myocardial energy metabolism in order to maintain a normal cardiac function. The development of myocardial infarction and heart failure is associated with the alterations in energy metabolism. It is a new therapy approach of myocardial infarction and heart failure optimizing myocardial energy metabolism, so it has important significance to clinical and experimental study on the therapy of energy metabolism. These research progress is reviewed in this article.

关 键 词：心肌梗死 能量代谢 心力衰竭 

分 类 号：R542.22[医药卫生—心血管疾病]