均匀表面增强活性基底上孔雀石绿的SERS  

SERS study of malachite green on uniform surface-enhanced substrate

作　　者：卜雅丽[1] 宦双燕[1] 刘湘江[1] 聂谨芳[1] 何卫民[1] 沈国励[1] 俞汝勤[1] 

机构地区：[1]湖南大学化学化工学院化学生物传感与计量学国家重点实验室,长沙410082

出　　处：《上海师范大学学报（自然科学版）》2008年第4期390-395,共6页Journal of Shanghai Normal University(Natural Sciences)

基　　金：国家自然科学基金(20605007)

摘　　要：利用自组装技术将50nm的纳米金吸附到修饰了聚乙烯吡咯烷酮(PVP)的玻片上,制备得到牢固的SERS活性基底.扫描电子显微镜(SEM)对其表面粒子形貌表征表明:形成了有序的单层吸附的纳米金粒子膜,无明显团聚现象.结合Raman mapping技术,以孔雀石绿这一禁用兽药为探针分子,观察了基底表面的SERS信号分布,计算得到各点信号的相对标准偏差低于10%.基底在水溶液中浸泡48h后,仍能保持较好的稳定性和高的SERS活性.结果表明:该基底制备简单,均匀性和重现性好,在水溶液中稳定性高,对孔雀石绿的检测限可达5×10-9mol.L-1.Through self- assembly technique, nano Au of 50 nm were adsorbed onto the polyvinylpyrrolidone （PVP） modified glass surface to achieve surface enhanced Raman scattering （ SERS）. SEM images revealed that the gold particles distributed uniformly to form the ordered monolayer with almost no evident aggregation, Malachite green, a prohibited animal drug, was used as probe molecule to investigate the SERS signal distribution by Raman mapping technique. The relatively standard deviation of the SERS responses on the substrate was lower than 10%. The substrate retained good stability and high SERS activity after being dipped in water for 48 h. The proposed substrate possessed the merits of easy preparation, uniform distribution, good reproducibility and strong stability against aqueous solution. The lowest detection limitation for malachite green was5×10^-9mol·L^-1.

关 键 词：孔雀石绿 表面增强拉曼光谱 纳米金 自组装 

分 类 号：O647[理学—物理化学]