基于计算机辅助工程技术测试人工机械心脏瓣膜血液动力学特性  

Hemadynamics properties of artificial mechanical heart valve based on computer aided engineering

作　　者：张向娟[1] 罗阳[1] 潘田佳[1] 刘云峰[1] 

机构地区：[1]四川大学制造科学与工程学院,四川省成都市610065

出　　处：《中国组织工程研究与临床康复》2008年第30期5849-5852,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：四川省2007年应用技术研究与开发项目(2007SGY053)~~

摘　　要：背景:目前对人工机械心脏瓣膜血液动力学性能的测试,大部分是通过实验装置完成的。实际上,通过使用计算机辅助工程技术,也可以方便地进行机械瓣稳态定常流模拟测试。目的:基于计算机辅助工程技术对双叶型人工机械心脏瓣膜的血液动力学特性进行测试。设计、时间及地点:观察性实验,于2006-09/2008-02在四川大学金工实验室完成。材料:在SolidWorks软件中建立的外径为23mm,内径19mm的双叶瓣模型。方法:按照国际标准ISO5840-2005规定的试验条件,使用SolidWorks软件中插件COSMOSFloWorks,对双叶瓣进行定常流和静态反流泄漏试验。主要观察指标:①双叶瓣不同流量下的跨瓣压差。②不同压力下静态反流泄漏值及反流百分比。③不同流量下平均跨瓣压差和有效开口面积。结果:模拟结果表明,双叶瓣跨瓣压差<20%,反流百分比<10%,有效开口面积2.379～2.858cm2。结论:通过计算机辅助工程技术来模拟人工机械心脏瓣膜的定常流测试结果符合设计要求,设置的模拟测试环境可以取代一部分模拟实验装置进行机械瓣的流体力学测试。BACKGROUND： Tests of artificial mechanical heart valve hemadynamics are performed mostly by experimental equipments. In fact, Computer Aided Engineering can be used to measure mechanical heart valve hemadynamics. OBJECTIVE： To test the hemodynamic performance of the bileaflet mechanical heart valve based on Computer Aided Engineering. DESIGN, TIME AND SETTING： The observational experiment was performed at the Goldsmith Laboratory of Sichuan University from September 2006 to February 2008. MATERIALS： Bileaflet mechanical heart valve of 23-mm external diameter and 19-mm inner diameter was established in SolidWorks software. METHODS： According to the International Standard ISO5840-2005, using COSMOSFloWorks, which is plugged SolidWorks software, steady flow and steady backflow leakage of bileaflet mechanical heart valve were examined. MAIN OUTCOME MEASURES： Pressure difference at different volume flow of bileaflet valve; Steady backflow leakage volume and regurgitant fraction at different pressure; Mean pressure differences and effective orifice areas at different volume flow. RESULTS： The transvalvular pressure drops of the bileaflet mechanical heart valve was less than 20%, percentage of regurgitation less than 10%, effective orifice areas ranged from 2.379-2.877 cm^2. CONCLUSION： By using Computer Aided Engineering technique, the analysis results of artificial mechanical heart valves are consistent with simulated results from experimental devices. The simulated test environment can be used to replace some experimental devices for hydromechanics test of mechanical prosthetic valve.

关 键 词：人工机械瓣膜 血液动力学 模拟试验 

分 类 号：R318[医药卫生—生物医学工程]