应变率显像评价左冠状动脉异常起源于肺动脉患者的左心室功能  

Assessment of left ventricular function by strain rate imaging in patients with anomalous origin of the left coronary artery from the pulmonary artery

作　　者：吴力军[1] 张玉奇[2] 孙锟[2] 衣晓蕾[2] 倪金洪[1] 高玲玲[1] 郁怡[1] 汪洁[1] 

机构地区：[1]上海交通大学医学院附属新华医院心超室,上海200092 [2]上海交通大学医学院附属上海儿童医学中心心内科,上海200127

出　　处：《中国临床医学影像杂志》2008年第8期544-546,590,共4页Journal of China Clinic Medical Imaging

基　　金：上海市浦东新区科技发展基金资助(编号:PKJ2006-Y08)

摘　　要：目的:探讨应变率成像(SRI)技术估测左冠状动脉异常起源于肺动脉(ALCAPA)患儿手术前、后左心室功能变化的准确性。方法:研究对象为39例正常儿童和16例ALCAPA患儿。应用SRI技术估测左心室不同心肌节段的应变及应变率值,并将16例ALCAPA患者手术前、后的应变值与正常儿童对比。结果:ALCAPA患者手术前收缩期及舒张期应变率及应变均低于正常儿童(P<0.01),手术后左心室收缩期及舒张期应变率及应变明显好转(P<0.01),但仍低于正常儿童(P<0.05)。结论:AL-CAPA患者的左心功能较正常儿童差,早期行冠状动脉移植术可以改善患者的心功能;应用SRI技术可以比较准确地估测AL-CAPA患者手术前后的心功能变化。Objective： To explore the accuracy of strain rate imaging （SRI） in quantitative assessment of left ventricular function in patients with anomalous origin of the left coronary artery from the pulmonary artery （ALCAPA）. Methods Thirtynine healthy subjects and 16 children with ALCAPA were studied. Regional strain rate in the mid, basal and apical segment of left ventricular wall and septum in systolic, early diastolic and late diastolic period and the systolic strain were measured, and these data were compared and analyzed. Results： The parameters of systolic strain and strain rate, diastolic strain and strain rate in the ALCAPA group before operation are significantly lower than that in the normal group（P〈0.01）. After coronary reimplantation, these parameters increased more significantly （P〈0.01）, but still lower than that in the normal group （P〈0.05）. Conclusions： Compared with normal children, left ventricular function is impaired in patients with ALCAPA, coronary reimplantation should be performed early to improve ventricular function. The change of left ventricular function before and after operation in patients with ALCAPA could be accurately assessed by strain rate imaging.

关 键 词：冠状动脉疾病 超声心动描记术 多普勒 彩色 

分 类 号：R543.3[医药卫生—心血管疾病] R540.45[医药卫生—内科学]