西乐葆和曲马多联合应用减少隆乳术后疼痛  

Application of Celecoxib and Tramadol in reducing pain from augmentation mammaplasty

作　　者：吕远东[1] 刘嘉琦[2] 陈伟华[1] 

机构地区：[1]哈尔滨医科大学附属第一临床医学院整形美容科,黑龙江哈尔滨150001 [2]哈尔滨医科大学附属第一临床医学院妇产科,黑龙江哈尔滨150001

出　　处：《中国美容整形外科杂志》2008年第4期280-282,共3页Chinese Journal of Aesthetic and Plastic Surgery

摘　　要：目的探讨西乐葆和曲马多联合应用减少隆乳术后疼痛的效果。方法采取随机实验方法,将100例患者分为两组,每组50例。A组为术后患者疼痛时服用曲马多片50mg;B组为术前2h口服西乐葆片400mg及术后每天早晨口服西乐葆片400mg,连服5d,在术后疼痛时再口服曲马多片50mg。统计两组患者服用曲马多片的总剂量,用数字评定量表进行疼痛评价,并统计患者术后出现的并发症。结果两组患者的年龄、假体体积、手术时间、术后感染和血肿发生率比较,差异无统计学意义。两组患者的曲马多用量、平均疼痛数值、恶心、呕吐的总天数比较,差异有统计学意义(P<0.05)。结论西乐葆和曲马多联合应用,可以降低术后平均疼痛数值,减少患者术后恶心、呕吐的发生率,促进术后恢复。Objective To explore the combined effect of Celecoxib and Tramadol on reducing pain from augmentation mammaplasty. Methods One hundred patients who underwent augmentation mammaplasty were randomly divided into 2 groups. Group A （n = 50） was treated with 50 mg Tramadol when they were suffering the pain after surgery. Group B （ n = 50） were applied with 400 mg Celecoxib which was taken orally at 2 hours before surgery and each morning after surgery for consecutive 5 days, took 50 mg Tramadol when they were suffeting the pain after surgery. The total dose of Tramadol in 2 groups was recorded, pain was evaluated using a Likert pain scale. Incidence of complications wwas recorded. Results There were no statistical differences between Group A and B in patient age, implant volume, total operative time, or the incidence of complications such as hematoma and infection. There was significant statistical difference between Group A and B in the dosage of Tramadol, average pain scale score, and days of nausea and vomit （P 〈 0.05）. Conclusion The combined ap- plication of eelecoxib and tramadol in reducing pain from augmentation mammaplasty can significantly reduce postoperative pain, vomit and nausea, improve the quality of a patient＇s postoperative recovery.

关 键 词：西乐葆 曲马多 疼痛 隆乳术 

分 类 号：R655.8[医药卫生—外科学]