佛山地区中老年人骨密度测定及骨质疏松患病率分析  

Epidemiological investigation of bone mineral density in normal middle-aged and old people in Foshan

作　　者：张盘德[1] 冯彦林[1] 张自茂[1] 

机构地区：[1]佛山市第一人民医院,佛山528000

出　　处：《中国骨质疏松杂志》2008年第8期567-569,共3页Chinese Journal of Osteoporosis

基　　金：佛山市科技发展专项资金项目(2004012)

摘　　要：目的了解佛山地区中老年人群骨密度（BMD）变化规律及骨质疏松（OP）患病率,为本地区骨质疏松症的防治提供参考。方法使用美国Hologic公司双能X线骨密度仪对839例广东省佛山地区40～85岁中老年人正位腰椎和股骨近端进行骨密度测定。结果随着年龄的增加（40岁以上）,男女性各部位BMD逐渐下降,女性更为明显,男性腰椎BMD下降程度较轻。男性腰椎50～岁组与60～岁组比较和60～岁组与70～岁组比较、女性腰椎60～岁组与70～岁组比较,差异无统计学意义（P〉0.05）,其余各组比较差异有显著性意义。腰椎的OP患病率最高,40~59岁男女患病率差异无显著性,60岁以后女性明显高于男性（P〈0.001）。40～84岁人群腰椎和股骨骨质疏松症发病率男性为27.1%和2.2%,女性为46.4%和11.8%,男女比较差异有非常显著性（P〈0.001）。结论佛山地区中老年人群BMD逐年下降,腰椎骨质疏松的患病率最高,研究的重点在中老年妇女。中老年人应坚持适当的体育活动,并注意防止跌倒导致的骨折发生。Objective To analyse the regularities of change in bone mineral density （BMD） and the prevalence rate of osteoporosis （OP） in Foshan district of Guangdong Province. Methods The BMD of lumbar （L1- L4 ） and proximal femur was measured by Hologic Delphi dual energy X-ray absorptiometry （DEXA） for 839 healthy people, 414 men, 425 women, aged 40 to 84 years. All data of BMD were compared and statistically analyzed. Results The BMD decreased gradually with increasing age （more than 40 years old）, bone loss was more sharply decreased for females. The difference of lumbar BMD between 50 ~ and 60 ~ years old and 60 ~ and 70 ~ years old for males, 60 ~ and 70 ~ years old for females were not significant （ P 〉 0.05）. The difference between other groups was significant. The prevalence rate of OP in lumbar was higher than proximal femur. The difference between 40 ~ 59 years old males and females was not markedly, the morbidity of OP in 60 years old and above females was higher than males（ P 〈 0.001 ） . The morbidity of OP of lumbar and proximal femur in all men and women was 27.1% , 2.2% and 46.4% , 11.8% respectively（ P 〈 0.001） .Conclusion The prevalence rate of OP in lumbar was higher in Foshan district. The study of OP is important for females but should not be ignored in males. Middle-aged and old people should be careful to avoid fall and fracture.

关 键 词：骨密度 骨质疏松症 患病率 

分 类 号：R181.3[医药卫生—流行病学] R814.4[医药卫生—公共卫生与预防医学]