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作 者:林志芳[1] 岑丽莲[1] 李海珠[1] 李南洋[1] 姚艺雄[1]
机构地区:[1]肇庆市第一人民医院,526021
出 处:《中国实用医药》2008年第22期14-15,共2页China Practical Medicine
摘 要:目的探讨2型糖尿病(D2m)患者血清肿瘤标志物CA125和CA199含量变化及临床意义。方法用化学发光法测定100例正常人和110例D2m患者血清中CA125和CA199含量。结果正常对照组CA125含量为(11.5±4.1)U/ml,CA199含量为(10.8±3.5)U/ml;D2m患者血清中CA125含量为(20.6±10.6)U/ml,阳性率为13.6%,CA199含量为(12.1±4.0)U/ml,阳性率为0.9%。结论D2m患者血清肿瘤标志物CA125含量较正常对照组增高(P<0.05),而CA199则无显著性差异。CA125升高可见于非恶性疾病。Objective To explore the serous concentration and clinical significance of tumor marker CA125 and CA199 in the patients with diabetes mellitus 2 ( D2 m). Methods The serous concentration of CA125 and CA199 were detected in 110 D2 m patients (D2 m group), 100 normal persons as control group. Results The serous concentration of CA125 and CA199 was respectectly (11.5±4.1) U/ml and (10.8±3.5) U/ml in control group, and (20.6±10.6) U/ml ( positive ratio 13.6% ), ( 12.1±4.0) U/ml ( positive ratio 0.9%) in D2 m group. Conclusion The serous concentration of CA125 in patient with D2 m is higher, compared with control group (P 〈 0. 05 ), and there is no significant in CA199. The high concentration of CA125 can appear in the nonmagnifiant diseases.
关 键 词:2型糖尿病 肿瘤标志物CA125 CA199 非恶性疾病
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