肾上腺素在慢性阻塞性肺病伴急性左心衰竭病人的疗效分析  

Effect of epinephrine on patients with acute exacerbation of chronic obstructive pulmonary disease with acute left ventricular failure

作　　者：何均[1] 赵琼芬[1] 

机构地区：[1]大英县人民医院,四川大英629300

出　　处：《西部医学》2008年第5期998-998,1000,共2页Medical Journal of West China

摘　　要：目的观察肾上腺素在慢性阻塞性肺病(COPD)加重期急性左心衰竭病人的治疗效果。方法将COPD加重期急性左心衰竭病人26例随机分为肾上腺素治疗组和西地兰治疗组,肾上腺素组12例,给予不少于1/3支(每支1mg)的肾上腺素肌注治疗(心音弱者1/3支,极弱1/2支,消失1支);西地兰组14例,给予西地兰0.2mg+5%葡萄糖10ml在5分钟内推入,以用药开始后15分钟为时间点监测心音强弱的改善程度,明显增强为显效,增强为有效,无变化为无效。结果肾上腺素组中显效10例,有效1例,无效1例;西地兰组中显效4例,有效6例,无效4例,两组急性左心衰治疗效果差异有显著性(P<0.01)。结论肾上腺素可以用作COPD加重期伴急性左心衰竭病人的心衰改善药物。Objective To investigate the effect of epinephrine in patients with acute exacerbation of chronic obstructive pulmonary disease （COPD） with acute left ventricular failure. Methods 26 patients were randomly divided into two groups, including epinephrine group （12 patients） and deslanoside grup （14 patients）. Epinephrine group was treated with epinephrine. Deslanoside group was treated with deslanoside. Results Therapeutic effects were divided into excellent, good and bad. 10, 1 and 1 cases of patients in epinephrine demongstrated excellent, good, and bad effect, respectively, but 4, 6 and 4 cases of patients in deslanoside demongstrated excellent, good, and bad effect, respectively. There was significant difference between two groups （μ=4.56 （P〈0. 01）. Conclusion Epinephrine may be an effective medicine for patients with acute exacerbation of chronic obstructive pulmonary disease with acute left ventricular failure.

关 键 词：肾上腺素 慢性阻塞性肺病加重期 急性左心衰竭 

分 类 号：R541.5[医药卫生—心血管疾病]