类风湿性关节炎患者血清新喋呤、可溶性IL-2R的测定及临床意义  

Studies Neopterin, Soluble Interleukin-2 Receptor in Serum on Rneumatoid Arthritis

作　　者：陈健[1] 金忠棋[1] 周游[1] 周沈贤[1] 林洁[2] 

机构地区：[1]浙江医科大学附属二院,310009 [2]浙江医科大学邵氏医院

出　　处：《伤残医学杂志》1997年第2期24-25,共2页Medical Journal of Trauma and Disability

摘　　要：为早期诊断类风湿性关节炎，提高治愈率，降低致残率，笔者检测了142例类风湿性关节炎患者和200例献血员（对照组）血清新喋呤、可溶性IL-2R水平．结果表明：142例类风湿性关节炎患者组的血清新喋呤和可溶性IL-2R水平分别为26．12±0.94ng／ml和435.43±22．59μ／ml，而对照组仅为＜10ng／ml和＜250μ／ml．经统计学检验．两者呈显著性差异（P＜0.001），提示血清新喋呤、可溶性IL-2R测定可用于早期鉴别急性类风湿性关节炎的诊断．Neopterin (NPT), soluble interleukin-2 receptor (SIL-2R) in serum have beendetermined by an enzyme linked immunosorbent assay (ELISA) in 142 specimens in order to research thesensible mark in earily diagnosis rheumatoid arthritis (RA). As a control group, 200 donators were alsoobserved. The result showed that NPT and SIL-2R respectively were 26.16 ±0.94ng/ml, 435.43±22.59μ/ml in RA. Below 10ng/ml, 250μ/ml in normal controls, NPT and SIL-2R were significantlyrising in RA (P<0.001). This work comes to the conclusion that NPT. SIL-2R may be play animportant roles in the diagnosis of acute RA.

关 键 词：类风湿性关节炎 新喋呤 可溶性IL-2R 测定 

分 类 号：R593.220.4[医药卫生—内科学]