夏枯草中的黄酮类化合物研究  

Studies on Flavonoids in Prunella vulgaris

作　　者：王祝举[1] 唐力英[1] 付梅红[1] 赫炎[1] 方婧[1] 

机构地区：[1]中国中医科学院中药研究所,北京100700

出　　处：《时珍国医国药》2008年第8期1966-1967,共2页Lishizhen Medicine and Materia Medica Research

摘　　要：目的研究夏枯草的药效成分。方法利用硅胶柱色谱法等对夏枯草进行分离纯化,根据光谱数据分析和化学方法鉴定化合物的结构。结果分离鉴定了3个化合物,鉴定其分别为①槲皮素-3-O-β-D-葡萄糖苷;②橙皮苷,即5,7,3'-三羟基-4'-甲氧基二氢黄酮-7-O-α-L-吡喃鼠李糖基-(1→6)-β-D-吡喃葡萄糖苷;③芦丁。结论化合物②为首次从夏枯草中分离得到。Objective To study the constituents in the flower of Prunella vulgaris L.. Methods The herb was extracted and purified with the column chromatography on silica gel and Sephadex LH-20,identified by the spectrum analysis and chemical method. Results 3 compounds were isolated from the plant , and their structures were elucidated as （1）quercetin - 3 - O - β - D - glucoside,（2）hesperidin and （3）rutin, Conclusion Compound（2） was isolated for the first time from Prunella vulgaris L.

关 键 词：夏枯草 黄酮苷 化学成分 

分 类 号：R284.1[医药卫生—中药学]