生物降解聚合物的研究和产业化进展及展望  

Progress and Prospects on the Academic Research and Industrial Application of Biodegradable Polymers

作　　者：李孝红[1] 袁明龙[2] 郝建原[3] 周绍兵[1] 邓先模[4] 黄志镗[5] 

机构地区：[1]西南交通大学材料学院、材料先进技术教育部重点实验室,成都610031 [2]四川琢新生物材料研究有限公司,成都610041 [3]电子科技大学微电子与固体电子学院,成都610054 [4]中国科学院成都有机化学研究所,成都610041 [5]中国科学院化学研究所,北京100080

出　　处：《高分子通报》2008年第8期109-122,共14页Polymer Bulletin

基　　金：国家自然科学基金(2870264、29070211、29434020、39470653、59473009,29774034、29934062、20004009、50303018,30570501、50603025、50773065、20774075);国家863计划(THC.97061);国家973计划(G1999064703)的支持.

摘　　要：结合作者等近十年来在生物降解聚合物领域的研究和产业化工作,本文概述了聚乳酸、聚氨基酸、聚对二氧六环酮及其它生物降解聚合物的合成进展,综述了可生物降解温度敏感水凝胶、形状记忆高分子材料的研究概况,阐述了可生物降解聚合物在生物活性大分子控释体系、超细纤维组织工程支架上的应用研究,介绍了可生物降解聚合物在食品包装、纺织和汽车电子等方面的应用,总结了可生物降解聚合物、医疗器械、药物制剂和组织工程等领域产业化近况。最后展望了生物降解聚合物的研究、应用和产业化前景。Biodegradable polymers have attracted much attention in biomedical, packaging, textile and electronic fields due to the degradability into harmless products after the end uses. The progress in the synthesis of ploylactide,poly（amino acid） and poly （p-dioxone）, and the further uses as biodegradable temperature-sensitive hydrogels and shape-memory polymers were reviewed. The applications of biodegradable polymers as carriers for bioactive macromolecules and fibrous scaffolds for tissue engineering were clarified in detail. The commercialization of biodegradable polymers, medical devices, drug formulations and tissue engineering was briefly introduced. Finally,the prospects on the academic research and industrial applications of biodegradable polymers were provided.

关 键 词：生物降解聚合物 生物医用 进展 展望 

分 类 号：O631[理学—高分子化学]