食管癌术后病人自控镇痛临床观察  

Clinical Observation to Patient-Controlled-Epidural-Analgesia(PCEA)after Esophagus Cancer Operation

作　　者：李荷亭[1] 

机构地区：[1]郑州师范高等专科学校,郑州450044

出　　处：《中国医药导刊》2008年第5期663-664,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:观察食管癌手术采用硬膜外阻滞经静吸复合全麻与术后病人自控硬膜外镇痛(PCEA)不同药物配比的止痛效果。方法:50例40～75岁 ASAⅠ-Ⅱ级开胸手术的食管病人,随机分为2组。A 组:(n=25)用药:0.75%布比卡因20ml、吗啡10mg、氟哌利多10mg 加生理盐水至100ml。B 组:(n=25)用药:0.75%布比卡因20ml、芬太尼0.4mg、氟哌利多10mg 加生理盐水至100ml。对比术后止痛效果并分别于手术当天、术后1、2天随访。结果:A 组病人按键次数少,用药量少;B 组病人按键次数多,用药量多。结论:A 组病人镇痛效果好,皮肤瘙痒、恶心呕吐发生率高;B 组病人病人镇痛效果稍差但是副作用发生率低。Objective ：To observe the analgetic effect of different medicine allocated proportion after Esophagus cancer operation. Methods： 50 esophagus cancer patients from 40 years old to 75 years old in ASAⅠ-Ⅱ level who had done open-chest operation, dividing them in to 2 groups at random, group A（n =25） dose： 0. 75% Bupivacaine 20ml, Morphine 10mg, Droperidol 10mg plus normal saline solution to 100ml. Group B ： （ n = 25 ） dose ： 0. 75% Bupivacaine 20ml, Fentany10. 4rag, Droperidol 10mg plus normal saline solution to 100ml compare the analgetic effect and apply it to the day when clinical operation did, revisit after 1 or 2 days. Results： the patients in group a press button few time, small dose. The patients in group b press button for many times, and have big dose. Conclusion ： the analgetic effect in group A is better, but skin pruritus, Disgusting vomit happens frequently. The analgetic effect in group B is so-so, but side effect is less.

关 键 词：食管肿瘤 病人自控镇痛 

分 类 号：R614[医药卫生—麻醉学]