氟喹诺酮类使用病例院感危险因素分析  

The Study of the Nosocomial Infection Risk Fact in the Fluoroquinolones Therapy Cases

作　　者：黄素丹[1] 温建红[1] 姚吐娟[1] 赖春霞[1] 辜素蓉[1] 

机构地区：[1]广东医学院附属南山医院药剂科院感科, 深圳518052

出　　处：《中国临床实用医学》2008年第8期36-37,共2页China Clinical Practical Medicine

基　　金：深圳市科技局科技项目（项目编号：200703188）;国家版权局专利（项目编号：软著登字第063668号,登记号：2006SR16002）

摘　　要：目的分析氟喹诺酮类抗菌药物的使用与医院感染发生的相关性，为抗菌药物的合理使用提供依据。方法通过本院“基于HIS的医院防保信息一体化管理系统”，对氟喹诺酮类抗菌药物使用病例的信息进行提取并进行统计学分析。结果氟喹诺酮类使用病例中有15例发生医院感染，感染率为13．16％，其他病例的院感率为3．05％，两者院感率差异有统计学意义。引起院感的危险因素是氟喹诺酮类用药时间过久和合并使用抗菌药物种类过多。Objective To analyze the relativities between the fluoroquinolone therapy and the nosocomial infection to prove the reasonable use of the antibiotics. Methods Using the system of ＂The integrative administration system of hospital preventive and health care medicine information based on the HIS＂, we can abstract and statistic analyze the messages of the cases remedied with fluoroquinolones. Results Totally 15 cases of nosocomial infection were found, the percentage is 13.16%. The nosocomial infection rate in other cases is 3.05%. There is statistic difference between these two nosoeomial infection. The risk faets causing the nosocomial infection are the longer time using fluoroquinolones and too many types of antibiotics using in these cases.

关 键 词：氟喹诺酮类 合理用药 医院感染 

分 类 号：R96[医药卫生—药理学]