射频联合紫衫醇+卡铂方案治疗晚期非小细胞肺癌的临床观察  

Addition of Cluster Electrode Radiofrequency Ablation (RFA) to Paclitaxal plus Carboplatin (PC) for Advanced NSCLC:Clinical Observation

作　　者：张红梅[1] 冯威健[1] 周蕾[1] 姜妮[1] 赵艳杰[1] 曹艺[1] 

机构地区：[1]北京大学世纪坛医院肿瘤中心,北京市100038

出　　处：《中国医院用药评价与分析》2008年第7期540-542,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:观察多极射频消融(RFA)联合紫衫醇+卡铂方案(PC)治疗晚期非小细胞肺癌(NSCLC)的临床效果。方法:30例晚期NSCLC(Ⅲ、Ⅳ期)采用RFA联合PC方案治疗,并与28例单纯PC方案化疗进行比较。结果:以疗效、生活质量评分及生存时间等指标评价,RFA联合PC方案治疗组明显优于单纯PC方案化疗组,疗效差异有显著意义,P<0.01。结论:RFA联合PC方案化疗明显提高晚期NSCLC治疗效果,可作为晚期NSCLC的综合治疗方法。OBJECTIVE： To observe the clinical efficacy of Cluster Electrode Radiofrequency Ablation （RFA）in combination with Paclitaxal plus Carboplatin （PC）for advanced Non - small Cell Lung Cancer （NSCLC） . METHODS： 30 patients with advanced NSCLC of stage Ⅲ and stage Ⅳ were treated with RFA and PC combination therapy, the results were compared with those underwent PC chemotherapy alone （n = 28）. RESULTS ： The RFA and PC combination therapy group was superior to the PC group in therapeutic effect, the life quality scores and the survival time, and there was a statistical significance in the therapeutic effects between the two groups （P 〈 0.01 ）. CONCLUSION： The RFA and PC combination therapy can improve the therapeutic efficacy in patients with advanced NSCLC and it can serve as a new comprehensive therapy in the treatment of advanced NSCLC.

关 键 词：肺癌 射频治疗 紫衫醇+卡铂方案 综合治疗 

分 类 号：R979.1[医药卫生—药品]