哮喘儿童使用吸入性糖皮质激素安全性评价  

Evaluation of the Safety of Inhaled Corticosteroids for Childhood Asthma

作　　者：王凤华[1] 周武杰[2] 翟所迪[1] 胡永芳[1] 

机构地区：[1]北京大学第三医院,北京市100083 [2]内蒙古医学院第三附属医院,包头市014030

出　　处：《中国医院用药评价与分析》2008年第8期580-582,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的：评价常用吸入性糖皮质激素在哮喘儿童中使用的安全性。方法：检索1998-2008年国内外文献,从肾上腺皮质功能、生长发育、骨代谢3个不同角度评价儿童使用吸入性糖皮质激素的安全性。结果：短期使用吸入性糖皮质激素对儿童的生长发育会产生一定影响;但从长期来看,安全性较高。结论：吸入性糖皮质激素的安全性和有效性之间能够达到一个平衡,可按GINA方案选择长期吸入激素治疗儿童哮喘。OBJECTIVE： To assess the safety of inhaled corticosteoids for childhood asthma. METHODS： The pertinent literature during 1998 -2008 both at home and abroad were retrieved, and the safety of inhaled corticosteoids for childhood asthma was assessed from the three aspects： adrenocortical function, growth and development, and bone metabolism. RESULTS： Treatment of childhood asthma with short - term inhaled corticosteroids could influence the growth and development of children, yet it was safe in a long run. CONCLUSION ： Safety and efficacy of inhaled corticosteoids can maintain equilibrium, and it is advisable to follow GINA plan in the treatment of childhood asthma in which the inhaled corticosteoids should be should for a long term.

关 键 词：吸入性糖皮质激素 儿童哮喘 安全性 

分 类 号：R977.11[医药卫生—药品]