体重指数在64层螺旋CT心脏扫描X线剂量管理中的应用研究  被引量:25

Dose reduction in coronary artery imaging with 64-row multi.slice helical CT with body mass indexdependent mA selection

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作  者:高建华[1] 王贵生[1] 郑静晨[1] 李剑颖[1] 孙宪昶[1] 高彩宏[1] 戴汝平[2] 

机构地区:[1]武警总医院CT科,北京100039 [2]中国医学科学院中国协和医科大学心血管病研究所北京阜外心血管病医院放射科

出  处:《中华放射学杂志》2008年第8期877-882,共6页Chinese Journal of Radiology

摘  要:目的在64层螺旋CT(64-MSCT)心脏检查中,通过对不同体重指数(BMI)采用不同管电流的研究,达到均衡控制X线剂量的目的。方法实验分2个步骤:(1)连续选取100例(C组)不同BMI拟行64-MSCT冠状动脉造影的患者,使用GELitghtSpeed VCT机完成心脏扫描。采用640mA,120kV,0.35s/r,层厚0.625mm,螺距0.22~0.24,选用体部前置滤线器模式,后置过滤器(C2)重建。采像后,在主动脉分出冠状动脉左主干层面的上下3层,分别选取面积相等的感兴趣区(10mm×10min)测量图像噪声,取3层CT值的标准差的平均值作为该患者的图像噪声。使用软件拟合患者BMI与噪声的关系,得出线性方程,根据噪声和射线剂量的关系,得到管电流与BMI的对应公式。(2)连续选取100例(L组)拟行64-MSCT冠状动脉造影的患者,先计算其BMI,并选定图像噪声常数27为可接受噪声,根据之前得到的BMI与管电流的对应公式确定mA值,选用心脏前置滤线器模式,开启心电图电流调控,C2重建。其他扫描参数不变,并以相同方法测量图像噪声。(3)应用SPSS10.0软件分别对第1步、第2步实验得到的BMI、心率、图像质量评分、图像噪声、CT剂量指数(CTDI)、有效剂量(ED)均值进行单因素方差分析。结果(1)C组BMI25.08±2.64,图像质量(3.71±0.54)分,噪声24.56±5.03,ED(17.63±1.68)mSv。拟合不同BMI和噪声得出曲线回归公式,根据射线剂量和噪声关系,得出电流随BMI变化的关系:常规管电流(FmA)×[(k1×BMI+C1)/INa]^2,FmA=640mA,常数(k1):1.033,截距(c1)=-3.2,噪声(INa)=27。(2)L组BMI25.07±2.91,图像质量(3.69±0.53)分,噪声26.61±3.44,管电流(469.95±113.45)mA,ED(9.08±2.25)mSv。L组噪声高于C组(F=927.390,P=0.001),但图像质量评分差异无统计学意义(FObjective To evaluate the robustness of body mass index (BMI) adapted tube current selection method for obtaining consistent image quality in MSCT coronary artery imaging. Methods Initially one hundred patients in the control group (C group) underwent cardiac scans using GE 64-row VCT with standard scan protocol (640 mA, 120 kV, 0. 35 sec, body bowtie, C2 filter). Noise measurement was obtained for each patient using the average of three consecutive slices in the ascending aorta with ROI of 10 mm × 10 mm to establish the relationship between BMI, desired image noise (IN) and required mA. An excel table was established to predict the required mA to achieve a desired IN for each patient with different BMI. A second group of one hundred cardiac patients ( L group) was scanned with BMI-adapted mA from the table to evaluate the practicability of this method. BMI,IN,CT dose index(CTDI) ,effective dose (ED) were all recorded. Results For the control group of 100 patients , the mean values and standard deviations of image quality score (IQS), BMI, IN and ED were 3.71 ±0.54, 25.08 ±2.63, 24.56 ±5.03 and (17.63 ± 1.68 ) mSv (with range of 15-22 mSv ). Regression analysis indicated linear relationship between BMI and image noise with fixed mA. Using the relationship between tube current and image noise and noise ratio between large bowtie and cardiac bowtie, the following equation for the required tube current Xma to achieve present image noise of INa for patient with certain BMI value when using cardiac bowtie could be then obtained : Xma = Fma × [ ( k1 × BMI + c1 )/Ina] ^2, where Fma = 640 mA, k1 = 1. 033, c1 = -3.2, INa = 27 in the study. (2) For the patients in L group, the mean values and standard deviations of IQS, BMI, and IN were 3.69 ± 0. 53, 25.07±2.91, and 26. 61 ±3.44, respectively. The average tube current used was (469.95 ± 113.45) mA, depending on patient's BMI values. The average effectively dose was( 9. 08 ±2.25) mSv. There was no sta

关 键 词:体重与身体测量 冠状血管 辐射剂量 

分 类 号:R686[医药卫生—骨科学]

 

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