含吡啶基胆固醇类小分子有机胶凝剂的合成及其胶凝行为  

Synthesis and Gelation Behavior of Pyridine-Containing Cholesterol-Based Low Molecular Mass Organic Gelators

作　　者：张秋红[1] 刘凯强[1] 刘静[1] 薛敏[1] 彭军霞[1] 房喻[1] 

机构地区：[1]应用表面与胶体化学教育部重点实验室,陕西师范大学化学与材料科学学院,西安710062

出　　处：《应用化学》2008年第9期1001-1006,共6页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金资助项目(20773083);教育部资助课题(20040718001)

摘　　要：合成了6种含吡啶基胆固醇类小分子胶凝剂。胶凝行为和SEM形貌观察研究表明,该类化合物结构的微小差异不仅显著影响自身的胶凝能力,而且对所形成的凝胶结构也有巨大影响。采用FT-IR和1H NMR测试分析表明,氢键作用是此类化合物凝胶形成的重要驱动力。采用XRD分析结果表明,2-位吡啶基的胶凝剂(化合物1)在固态时的堆积方式与其在苯中(凝胶态)的堆积方式类似,也与其对应的质子化形式在苯中(凝胶态)的堆积方式相似,且各聚集体的最小重复单元均为2.58 nm。New cholesterol-based low molecular mass organic gelators bearing a 2-, 3-, or 4- pyridyl unit, which are denoted as 1, 2, and 3, respectively, have been synthesized, and their corresponding salts（1＇, 2＇, 3＇） have also been prepared by simply protonating them with HCl. It is revealed that both the gelation behavior of the gelators and the micro-structures of the xerogels strongly depend on the relative position of N atom in the pyridyl unit and the protonation state of the pyridyl unit. FT-IR and ^1H NMR studies demonstrate clearly that hydrogen bonding between the amide groups of the gelators play an important role in the formation of the organogels. XRD studies show that the primary assembly of compund 1 in benzene is similar to that of compund 1＇ in the same solvent, and furthermore is also similar to that of compund 1 in solid state. The repeat units of the three aggregates are almost the same, and are very close to the size of molecule 1.

关 键 词：小分子有机胶凝剂 凝胶 吡啶 胆固醇 

分 类 号：O648.1[理学—物理化学]