2种抗菌药物治疗急性细菌性感染的药物经济学评价  

Economical Evaluation of Treatment for Acute Bacterial Infection with Pazufloxacin and levofloxacin

作　　者：陈蓉[1] 许燕红[1] 

机构地区：[1]遵义医学院第五附属(珠海)医院,519100

出　　处：《青海医药杂志》2008年第8期5-7,共3页Qinghai Medical Journal

摘　　要：目的:评价帕珠沙星与左氧氟沙星治疗急性细菌性感染的成本-效果。方法:查阅文献,选择分别用帕珠沙星(A组)与左氧氟沙星(B组)治疗急性细菌性感染的病例240例,运用药物经济学成果-效果分析法进行分析和评价。结果:A组、B组临床总有效率分别为98.3%和96.7%;两组的成本分别为(4268.32±645.88)元、(1467.84±197.38)元;以临床总有效率计:A组、B组成果-效果比分别为43.42±6.57、15.18±2.04;A组相对于B组的增量成本-效果比为1750.30。结论:与帕珠沙星比较,左氧氟沙星治疗急性细菌性感染更具成本-效果优势。Objective： To compare the economical cost and effectiveness of treatment for antibiotic infection between Pazufloxacin, and levofloxacin.Methods：A total of 240 patients suffered from acute bacterial infection were treated with pazufloxacin （group A） and levofloxacin （group B） respectively. The data was analyzed and compared by effect of law. Results： The total effective rate of group A and group B was 98.3% and 96.7% respectively; the economical cost was 4 268.32 ± 645.88 yuan and 1467.84 ± 197.38 yuan and the cost/effect ratio was 43.42 ± 6. 57and 15.18 ± 2.04 respectively. Ratio of group A to group B in incremental cost was 1 750.30. Conclusions：There is a mere superior economical cost and effectiveness in treatment of bacterial infection with levofloxacin compared with that with pazufloxacin.

关 键 词：帕珠沙星 左氧氟沙星 急性细菌性感染 成果-效果分析 

分 类 号：R956[医药卫生—药学]