非ST段抬高急性冠状动脉综合征患者TIMI危险积分与血浆脑钠肽的相关性  

Relationship of TIMI risk score with plasma brain natriuretic peptide in patients with Non-ST segment elevation acute coronary syndrome

作　　者：苏洪亮[1] 陈玉敬 肖岳[1] 

机构地区：[1]界首市人民医院心内科,安徽省236500

出　　处：《中国心血管病研究》2008年第9期677-679,共3页Chinese Journal of Cardiovascular Research

摘　　要：目的探讨非ST段抬高急性冠状动脉综合征(NSTEACS)患者TIMI危险积分与血浆脑钠肽(BNP)水平的相关性。方法收集85例非ST段抬高急性冠状动脉综合征患者,以临床预测变量对其进行TIMI危险评分积分,并进行危险层次分层,酶联免疫吸附法检测患者血浆脑钠尿肽水平,分析其与TIMI危险积分不同层次之间的关系。结果血浆BNP水平与TIMI危险积分呈正相关(r=0.71,P<0.05);随着TIMI危险积分评分值增加,患者血浆BNP水平亦逐渐升高,随访期主要心血管事件发生率也增多(P<0.05)。结论TIMI危险评分与BNP水平呈正相关,并与NSTACS预后有关,能够对NSTEACS患者进行危险分层。Objective To investigate the correlation of TIMI risk score and plasma brain natriuretic peptide （BNP） in patients with non-ST segment elevation acute coronary syndrome. Methods Plasma brain natriuretic peptide were measured by enzyme-linked immune absorption assay（ELISA） in 85 patients with non-ST segment elevation acute coronary syndrome, and TIMI risk score were calculated. Results The TIMI risk score is positively correlated with the plasma BNP level （r=0.71 ,P〈0.05 ）. The incidence of MACE increased significantly with the rise of TIMI risk score and BNP level. Conclusion The higher TIMI risk score and BNP level, the worse the prognosis, it could be use to predict the prognosis.

关 键 词：急性冠脉综合征 非ST段抬高型 TIMI危险积分 脑钠尿肽 

分 类 号：R541.4[医药卫生—心血管疾病]