曲马多与西乐葆联合应用减少剖宫产术后疼痛  

Celebrex and tramadol reduce pain following uterine-incision delivery

作　　者：刘嘉琦[1] 王艳[1] 李静[1] 

机构地区：[1]哈尔滨医科大学附属第一临床医学院妇产科,黑龙江哈尔滨150001

出　　处：《中国妇幼保健》2008年第25期3619-3621,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨曲马多和西乐葆联合应用是否可以减少剖宫产术后疼痛。方法:采取随机方法将患者分为两组,每组50人;A组在术后患者疼痛时服用曲马多片;B组在术前2h及术后每天早晨服用西乐葆;且也在术后疼痛时口服曲马多片。统计曲马多片总量;两组患者用数字评定量表进行疼痛评价;统计患者术后并发症。结果:两组患者的年龄、妊娠周数、手术时间、术后出血及感染的发生率在统计学上没有显著的差异。A组患者曲马多用量、平均疼痛数值、恶心、呕吐的总天数与B组相比具有显著的差异(P<0.05)。结论:西乐葆和曲马多联合应用可以降低术后平均疼痛数值;减少患者术后恶心、呕吐的发生率;促进患者的术后恢复。Objective： To determine whether the combination of celebrex and tramadol can reduce pain following uterine - incision delivery. Methods： One hundred patients underwent uterine - incision delivery were randomly assigned to group A （ n = 50 ） to use tramadol as needed to control postoperative pain and group B （ n = 50） took celebrex orally 2 hours prior to surgery and then each morning following surgery. In addition, they were instructed to use tramadol as needed to control postoperative pain. All patients documented the number of tramadol they used daily for 5 days following surgery. At the same time, patients of both groups rated their own pain using a Likert pain scale. Incidences of complications were recorded. Pain was assessed daily. Results： There were no statistical variations between group A and B for patient age, pregnancy time, total operative time, or the incidence of complications such as hematoma and infection. There were significant statistical variations between group A and B for the dosage of tramadol, average pain scale score, and days of nausea and vomit （P 〈 0. 05） . Conclusion： The addition of celebrex to tramadol in patients undergoing uterine -incision delivery can significantly reduce postoperative pain, vomit and nausea to improve the quality of a patient＇s postoperative recovery and facilitate resumption of everyday activities.

关 键 词：西乐葆 曲马多 剖宫产术 疼痛 

分 类 号：R719[医药卫生—妇产科学]