下丘脑区病变术后血钠紊乱与癫痫的临床研究  

Clinical research of natremia disorders and epilepsy with hypothalamic lesions after surgery

作　　者：吴光明[1] 陈林[1] 吴博[1] 龙天霖 雷开明[1] 徐全华[1] 田斌[1] 

机构地区：[1]贵州省毕节地区医院神经外科,贵州毕节551700

出　　处：《中国现代医学杂志》2008年第16期2389-2391,共3页China Journal of Modern Medicine

摘　　要：目的研究下丘脑区病变术后血钠紊乱与癫痫的关系及治疗。方法观察术后发生癫痫情况。术前术后每日检测血钠,并根据其变化进行治疗。结果68例下丘脑区病变手术,42例(61.7%)发现血钠紊乱,其中9例(9/42)发生癫痫,占21.4%。血钠紊乱与癫痫发生率密切相关,血钠在12h内的变化幅度与癫痫发生关系更加密切。结论下丘脑区病变手术后血钠紊乱者发生癫痫可能性大,其中以交替性血钠异常者最易发生。血钠突然波动,尤其12h内的血钠急剧下降更易诱发癫痫。术后对血钠的监测并及时纠正,能有效的预防下丘脑区病变术后癫痫。[Objective] To study the relationship between the natremia disorders and epilepsy and treatment for the hypothalamic lesions after surgery. [Methods] Observed the incidence of epilepsy after surgery. Preoperative and postoperative detection of natremia every day,and in accordance with changes in their treatment. [Results] In 68 patients with hypothalamic lesions after surgery, 42 cases （61.7%） were found natremia disorder, nine cases （9/42） were found epilepsy （21.4%）. Natremia disorder is obviously related to the incidence of epilepsy,natremia in 12 h with the rate of change in the relationship between the incidence of epilepsy more nearly. [Conclusion] Hypothalamic lesions after surgery in natremia disorder is more possible for epilepsy, the turn of natremia abnormal is the most possible. The natremia fluctuations decreased suddenly especially in particular the 12 h decreased more rapidly induced epilepsy. Postoperative monitoring of the natremia and correcting promptly can be effective under the control of epilepsy after hypothalamic lesions.

关 键 词：下丘脑区 病变 血钠 癫痫 

分 类 号：R651.11[医药卫生—外科学]