肾细胞癌的超声造影研究  

Characterization of renal cellular carcinoma with contrast-enhanced ultrasound

作　　者：徐作峰[1] 万广生[1] 谢晓燕[1] 吕明德[2] 徐辉雄[1] 刘广健[1] 黄蓓[1] 

机构地区：[1]中山大学超声诊断与介入治疗研究中心中山大学附属第一医院超声科,广州510080 [2]中山大学超声诊断与介入治疗研究中心中山大学附属第一医院肝胆外科,广州510080

出　　处：《中华超声影像学杂志》2008年第8期694-696,共3页Chinese Journal of Ultrasonography

摘　　要：目的总结和探讨肾细胞癌的超声造影特征。方法70例肾细胞癌共72个病灶接受了常规超声和超声造影检查，分析病灶的常规超声及超声造影表现特征。超声造影使用造影剂声诺维和对比脉冲序列成像技术。结果常规超声显示低、等、高回声的病灶分别为44．4％（32／72）、25．0％（18／72）和30．6％（22／72）。病灶彩色血流信号显示率为38．9％（28／72），动脉峰值流速（43．7±16．8）cm／s（24．8～95cm／s），阻力指数0．63±0．11（0．53～0．80）。超声造影显示皮质期63个（87．5％）病灶表现为等或高增强，9个（12．5％）为低增强。63个等或高增强病灶中48个（76．2％）实质期及晚期减退至低增强，15个（23．8％）仍保持等或高增强。9个皮质期表现为低增强病灶、晚期仍为低增强。75．0％（54／72）病灶不均匀增强，内可见无增强区，87，5％（63／72）的病灶可显示代表假包膜的高增强环。结论超声造影病灶皮质期不均匀等或高增强，实质期或晚期呈低增强，以及假包膜增强是肾细胞癌的重要表现、能将有助于肾细胞癌的诊断及鉴别诊断。Objective To conclude the characterization of renal cellular carcinoma（RCC） with contrastenhanced ultrasound. Methods Seventy patients （seventy-two nodules） with RCC, which were confirmed by operation and biopsy underwent conventional ultrasound and contrast-enhanced ultrasound（CEUS）. Microbubble agents SonoVue and contrast pulse sequence（CPS） were used. The conventional ultrasonographic characterization and the enhancement patterns of lesions were analyzed. Results On baseline sonography,the numbers of lesions that showed hypoechogenicity, isoechogenicity, and hyperechogenicity were 44.4 % （32/72）, 25. 0% （18/72） and 30.6%（22/72）, respectively. Only 28 lesions （38.9%） showed flow signals on color Doppler sonography, the mean maximum velocity of which was（43.7 ± 16.8）cm/s （range,24.8-95 cm/s） ,and the mean resistance index was 0. 635 ±0.11 （range,0. 52-0. 83）. Sixty-three （87.5 % ） lesions were hyper-vascular in cortical phase. Among them forty-eight （76.2%） lesions were hypo-enhanced,and fifteen （23.8%） lesions were still hyper-vascular in late phase. The remaining nine hypervascular nodules in cortical phase were still hyper -enhancing in late phase. Fifty-four （75. 0%） lesions were inhomogeneous enhancement, and pseudocapsule was observed in sixty-three （87.5%） RCC lesions. Conclusions The enhancement patterns of RCC are characteristic, and CEUS may be helpful in differential diagnosis of focal renal lesions.

关 键 词：超声检查 微气泡 癌 肾细胞 

分 类 号：R686[医药卫生—骨科学]