近10年来克山病区高血压发病率的动态变化  

Prevalence and Detection Rate of Hypertension and Keshan-disease During Last Decade in Keshan-disease Epidemic Area

作　　者：张永瑞[1] 廖永建[1] 格鹏飞[1] 曹永琴[1] 司宏宗[1] 董彩霞[1] 

机构地区：[1]甘肃省疾病预防控制中心,甘肃兰州730020

出　　处：《中华高血压杂志》2008年第8期716-719,共4页Chinese Journal of Hypertension

摘　　要：背景与目的克山病是一种以扩张型心肌病为临床主要症状的地区流行病,原因不明。本文旨在分析近10年来国家级克山病监测点甘肃西和县杨庄高血压与克山病的的流行情况。方法按照《克山病监测方案》,每2年在该监测点开展1次普查,包括询问病史、测量血压、描记心电图等。连续跟踪13年。结果 1)杨庄克山病区13年累积的高血压总检出率(即患病率,下同)大于克山病检出率(高血压检出率13.4%比克山病检出率10.7%,x^2=8.555,P=0.002);2)克山病患者中高血压的患病率比非克山病人群高(Z=-2.43,P=0.015),克山病人群中高血压患病率增长速度明显高于非克山病人群,是非克山病人群的1.7倍(166.3%比99.1%);3)13年克山病检出率增长2.3倍,总增长速度132.8%,低于高血压增长速度;4))13年克山病地区原发性高血压检出率增长3.4倍,总的增长速度为240.0%,高于全国其他地区同期水平;女性与男性之间的差异无统计学意义。结论杨庄克山病检出率增长缓慢,但是高血压检出率增长迅速;高血压检出率增长迅速是否与克山病区地域及人群原有心血管患病有关,值得进一步研究。Background and Objective Keshan disease is clinically characterized as a dilated cardiomyopathy. We analyze the prevalence trend during last decade of hypertension and Keshan-disease in Yangzhuang village which was a Keshan-disease epidemic area. Method The survey including medical history, blood pressure and ECG were carried out every two years during the follow up 13 years. Results During follow up period, the total detection rate（hypertension： 13.4% vs Keshan-disease： 10.7 %, X^2= 8. 555, P= 0. 002） and the accumulative rate of hypertension were higher than those of Keshan-disease, which was on the contrary to that before 1993, when increasing rate of Keshan-disease was higher than hypertension. Furthermore, the accumulative increasing rate of hypertension was 240.0 %, which was higher than the national average level during corresponding period with no significant differences between female and male. Conclusion The detection rate of hypertension in Keshan disease epidemic area was higher than the average rate nation-wide. Whether the hypertension prevalence was related to Keshan-disease needs further investigation.

关 键 词：克山病区 高血压 动态观察 

分 类 号：R542.3[医药卫生—心血管疾病]