先天性腹裂治疗方式20年系统评价  

Systematic review of treatment method of gastroschisis in 1998～2007

作　　者：陈盛[1] 吴晔明[1] 洪莉[1] 赵海腾[1] 王宇鹏[1] 

机构地区：[1]上海儿童医学中心外科,200127

出　　处：《临床小儿外科杂志》2008年第4期11-15,共5页Journal of Clinical Pediatric Surgery

基　　金：2006年上海市卫生局基金资助项目;项目编号2006025

摘　　要：目的客观呈现20年来一期手术关腹和Silo技术分期修复治疗的先天性腹裂患儿存活情况。方法检索相关数据库,对两种方法治疗的腹裂患儿的存活率进行Meta分析,比较其差异。结果Meta分析显示,1988～2007年一期关腹组术后存活率高于Silo分期修复组,敏感性分析结果与之一致。亚组分析显示,1988～1997年两组存活率差异无统计学意义,1998～2007年一期关腹组存活率高于Silo分期修复组。结论1988～2007年一期手术关腹患儿术后存活率高于Silo技术分期修复。由于病例分组存在选择偏倚,难以得出一期关腹效果优于Silo技术分期修复的结论。Objective To present the survival rate of gastroschisis treated by primary closure （PC） and Silo staged closure （SC） in 1988 - 2007 by means of a systematic review. Methods Search related databases, do a meta-analysis on the survival rate of gastroschisis treated by these two methods, and compare the difference. Results Meta-analysis shows PC group has a higher survival rate than SC group in 1988 - 2007.Sensitive analysis has the same resuh.Subgroup analysis shows there is no statistical significance of survival rate in these two groups in 1988- 1997, but PC group has a higher survival rate than SC group in 1998-2007.Conclusious PC group has a higher survival rate than SC group in 1988 - 2007.But we can＇t conclude that PC is more effective than SC because of the selection bias.

关 键 词：先天性腹裂 症状 临床分析 治疗方法 

分 类 号：R726.5[医药卫生—儿科]