血液灌流对重度有机磷中毒急性期并发症的疗效观察与分析  

Observation and analysis on efficacy of hemoperfusion for acute phase complication of severe organophosphate poisoning

作　　者：陈小兵[1] 付平[2] 张戈[1] 

机构地区：[1]成都市龙泉驿区第一人民医院,四川成都610100 [2]四川大学华西附属一医院肾内科,四川成都610041

出　　处：《临床和实验医学杂志》2008年第9期52-53,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的观察血液灌流(HP)对重度有机磷中毒(AOPP)急性期并发症的临床疗效。方法回顾2005年8月至2007年7月收住我院的40例AOPP患者的临床资料,在常规治疗的基础上加HP。统计其急性呼吸衰竭、中间综合征、中毒反跳的发生率。结果本组40例中毒患者,急性呼吸衰竭、中间综合征、中毒反跳的发生率分别为7.5%、12.5%、15.0%。结论血液灌流治疗可降低重度有机磷中毒急性呼吸衰竭的发生率,但对中间综合征和中毒反跳的防治作用不显著。Objective To observe the clinical therapeutic effect of hemoperfusion for patients with acute phase complication of severe organophosphate poisoning. Methods Clinical data of 40 cases of severe organophosphate poisoning admitted during the period of August, 2005 to July, 2007 were retrospectively reviewed. The patients accepted hemoperfusion besides routine therapeutic methods. The incidence rates of acute respiratory, failure, intermediate syndrome and poison rebound were statistically analyzed. Results In 40 cases of severe organophosphate poisoning, the incidence rates of acute respiratory failure, intermediate syndrome and poison rebound are 7.5%, 12.5%, and 15.0% respectively. Conclusion Hemoperfusion can reduce the incidence rate of acute rspiratory failure, but its effect for prevention of intermediate syndrome and poison rebound is not significant.

关 键 词：血液灌流 有机磷中毒 急性期并发症 

分 类 号：R595.4[医药卫生—内科学] R563.8[医药卫生—临床医学]