重症颅脑损伤后脑性盐耗综合征的诊治策略  

Strategy of diagnosis and treatment for cerebral salt wasting syndrome after serious cerebral injury

作　　者：罗志毅[1] 周筠[1] 毋江 

机构地区：[1]郑州大学第一附属医院急诊科,450052 [2]河南省创伤急救中心

出　　处：《中国现代药物应用》2008年第18期4-5,共2页Chinese Journal of Modern Drug Application

摘　　要：目的探讨重型颅脑损伤患者并发脑性盐耗综合征的病因、发病机制、诊断及治疗经验。方法回顾性分析重型颅脑损伤后发生脑性盐耗损综合征的22例患者,通过其临床表现及实验室检查明确诊断,确定有效的治疗方法。结果除2例死于继发性疾病外,20例患者低血钠症状恢复。结果低血钠、高尿钠、低血容量及意识状态改变是脑性盐耗综合征的诊断依据,水化和补盐治疗安全有效。Objective To discuss the pathogenesis, pathology, diagnosis and treatment of cerebral salt wasting syndrome （CSWS） in serious cerebral injured patients. Methods Based on clinical presentation and laboratory results, 22 cases of CSWS after serious cerebral injury were analyzed retrospectively and the effective therapy was provided. Results In this series, 20 cases were cured and 2 died of secondary cerebral infarction. Conclusion Hyponatremia, hypernatruria, hypovolemia and changes of consciousness are main signs to diagnose CSWS. Hydration and salt replacement are safe and effective in the treatment of CSWS.

关 键 词：颅脑损伤 脑性盐耗综合征 临床分析 治疗方法 

分 类 号：R651.15[医药卫生—外科学]