Graves病伴肝损害22例临床特点分析  

Clinical features of hepatic injury in 22 patients with Graves'disease

作　　者：王午喜 何云[1] 张融[1] 朱爱东[1] 

机构地区：[1]重庆市第五人民医院内分泌科,重庆400062

出　　处：《重庆医科大学学报》2008年第9期1127-1129,共3页Journal of Chongqing Medical University

摘　　要：目的:探讨初诊弥漫性甲状腺肿伴甲状腺功能亢进(Graves病)肝损害的临床特点。方法:回顾性分析22例初诊Graves病伴肝损害患者(A组)的临床资料,并与22例肝功能正常的初诊Graves病患者(B组)比较。结果:A组患者ALT增高(95.5%)、AST增高(86.4%)、GGT增高(50.0%)、ALP增高(22.7%),明显高于B组(P<0.05);且A组年龄、病程、血FT3、FT4水平明显高于B组(P<0.05)。结论:初诊Graves病伴肝损害患者病程长、年龄大、血FT3和FT4水平高,尽早诊治Graves病,及时发现其肝损伤意义重大。Objective：To evaluate the clinical features of hepatic injury in the patients with Graves＇disease. Methods：Clinical records of 22 Graves＇disease patients with hepatic injury（group A）and 22 patients without hepatic injury（group B）were studied retrospectively. Results：In group A the ALT,AST,GGT and ALP increased significantly （P〈O.OS）.the group A was elder, the course of disease was longer and the serum level of and FT3 and FT4 were higher than group B. Concision：It is important to diagnose and treat the patients with Graves＇disease and hepatic injury.

关 键 词：GRAVES病 肝损害 

分 类 号：R581.1[医药卫生—内分泌]