砷、锑、铋配合物的生物活性  

Biological Activities of the Complexes of Arsenic,Antimony and Bismuth

作　　者：张志朋[1] 钟国清[1] 蒋琪英[1] 

机构地区：[1]西南科技大学化学系,绵阳621010

出　　处：《化学进展》2008年第9期1315-1323,共9页Progress in Chemistry

基　　金：四川省科技厅应用基础研究基金项目(No.05JY029-113)资助

摘　　要：合成新型砷、锑、铋的配合物并研究其构效关系与生物活性的作用机理,对于丰富生物无机化学内容、开发新的抗菌和治疗肿瘤的化学药物都具有重要的意义和价值。本文简要介绍了砷、锑、铋的化学性质,并综述了近年来砷、锑、铋的配合物在抗癌抗菌抗肿瘤等生物活性方面的应用,展望了其在该领域的应用前景。The complexes of arsenic, antimony and bismuth are used as antibacterial and antitumor drugs in the field of clinical medicine. It is significantly important to synthesize new arsenic, antimony and bismuth complexes and study on the inner relationship of their biological activities and structures. This paper briefly introduces the chemical properties of arsenic, antimony and bismuth, reviews the applications of their complexes in anti-cancer and antibacterial activities, and prospects the application potential in the future.

关 键 词：砷 锑 铋 配合物 生物活性 

分 类 号：O614.5[理学—无机化学] O621.29[理学—化学]