多级膜浓缩鼻炎康提取液的研究  

Concentration of biyankang extracts using multi-stageme mbranes separation

作　　者：罗吉 钟美好 肖凯军[2] 袁亮[2] 石浩[2] 

机构地区：[1]佛山德众药业有限公司,广东佛山528000 [2]华南理工大学轻工与食品学院轻化工所,广东广州510640

出　　处：《中国中药杂志》2008年第17期2108-2112,共5页China Journal of Chinese Materia Medica

基　　金：国家“十一五”科技支撑计划项目(2006BAD05A02);2006年粤港关键领域重点突破项目(20060107-2);广州市科技成果推广项目(2006C13G0011)

摘　　要：目的:改进鼻炎康复方提取液的提取工艺。方法:在室温下开展超滤-纳滤多级膜浓缩,采用高效液相色谱法测定鼻炎康提取液中主要有效成分在膜处理后的保留情况。结果:多级膜分离浓缩法可以去除鼻炎康提取液中45%左右的水分,成本为现有生产中真空浓缩加热法的1/4。提取液中主要有效成分蒙花苷的保留率在80%以上,盐酸麻黄碱的保留率在90%以上。结论:达到了较好的高效浓缩和节能效果,为鼻炎康复方提取液膜浓缩的现代化生产提供了理论指导和实验依据。Multi-stage membranes processes, including ultrafiltration and nanofiltration are used in concentration of Biyankang extracts at room temperature, and the concentrations of main active ingredient in retentions after membrane processes were determined by HPLC. The results showed that the removal rate of water is about 45%, and the cost is only one fourth of the vacuum heating method. The retention rates of buddleoside and ephedrine hydrocbloride are above 80% and 90% respectively, which meet the efficient concentration and energy-saving needs. The concentration method of Biyankang with multi-stage membranes processes provides some instructive theories and experimental foundations.

关 键 词：鼻炎康 超滤 纳滤 蒙花苷 盐酸麻黄碱 

分 类 号：R286[医药卫生—中药学]