急性冠状动脉综合征患者焦虑情绪对生活质量的影响  

Research on the relationship of anxiety symptoms to the quality of life in patients with acute coronary syndrome

作　　者：刘光辉[1] 徐颖[1] 马文林[1] 李美婧[1] 张俊蒙[1] 朱梦云[2] 胡大一[3] 

机构地区：[1]同济大学附属同济医院心内科,上海200065 [2]同济大学附属第10人民医院心内科 [3]北京大学人民医院心脏中心

出　　处：《临床心血管病杂志》2008年第8期600-602,共3页Journal of Clinical Cardiology

摘　　要：目的:调查急性冠状动脉综合征(ACS)患者焦虑情绪的患病率,了解其对患者生活质量的影响。方法:入选ACS患者454例,运用医院焦虑抑郁量表焦虑亚量表(HADS-A)评分分为焦虑组(HADa≥6分)和非焦虑组(HADa<6分),并使用SF-36对其生活质量进行评估。结果:454例中247例为焦虑组;207例为非焦虑组。患病率为54.4%;2组人群血脂及炎症因子水平差异无统计学意义(P>0.05);焦虑组全部生活质量评分均显著低于非焦虑组(P<0.01);HADS-A焦虑评分与患者生活质量评分呈显著负相关(P<0.01),进一步Logistic回归分析未见炎症因子与ACS患者焦虑的发生有明显相关性。结论:ACS患者焦虑情绪较为常见,使其生活质量明显降低。Objective： Anxiety is thought to be a common symptom in patients who suffer from acute coronary syndrome（ACS）. This study aims to present a general data about the anxiety symptoms in Chinese ACS patients, and evaluate the impact of anxiety symptoms on their quality of life （QOL）. Method：We enrolled 454 Chinese patients with ACS from SHANGHAI, whose baseline data were obtained within 1 week after hospital admission. The subseale of Chinese version of the Hospital Anxiety and Depression Scale（HADS-A） and SF-36 were used to assess anxiety and their QOL, respectively. All the participants were divided into 2 main groups： HADa≥6（n 247） and HADa〈6 （n=207）. Result：The 54.7% of 454 ACS patients met the criteria for anxiety. As to baseline characteristics, including the level of inflammatory factor and cholesterol, didn＇t show a significant difference between 2 groups （P〉0.05）. The participants from non-anxiety group had a better QOL than anxiety group （P〈0.01）. And anxiety was negatively associated with the QOL （P〈0.01）. Logistic regression analysis didn＇t suggest inflammatory factor is an important risk factor for anxiety of ACS patients. Conclusion：The study confirmed the western notion that anxiety is a common psychosocial problem, which also applies to Chinese patients diagnosed with ACS. Anxious ACS patients have rather worse quality of life.

关 键 词：急性冠状动脉综合征 焦虑 流行病学 

分 类 号：R542.2[医药卫生—心血管疾病]