脑干听觉诱发电位对婴儿肝炎综合征的监测及临床意义  

Clinical significance and monitoring of brainstem auditory evoked potential in infantile hepatitis syndrome

作　　者：罗慧[1] 吴惠玲[1] 

机构地区：[1]广州市儿童医院,510120

出　　处：《广州医药》2008年第5期39-40,共2页Guangzhou Medical Journal

摘　　要：目的探讨婴儿肝炎综合征（infant hepatitis syndrome，IHS）脑干听觉诱发电位（brainstem auditory evoked potential，BAEP）的变化及其临床意义。方法收集我院传染病区住院的婴儿肝炎综合征50例，年龄1～3月进行脑干听觉诱发电位（BAEP）检测，分析比较不同病因、胆红素对脑干听觉诱发电位的影响。并与本院保健门诊体检的同龄健康儿进行对照，将相关资料进行统计学（卡方检验）分析。、结果不同病因致胆红素升高均可影响脑干听觉诱发电位，各组间无明显差异（P〉0．05）；直接胆红素升高为主和间接胆红素升高为主之间比较，异常率无显著性差异（P〉0．05）；周围性损伤（80％）较中枢性损伤（20％）多见（P〈0．01）；观察纽异常率（65％）明显高于对照组（30．4％）（P〈0．01）。结论HIS患者可有较高比例脑干听觉传导通路障碍。对婴肝儿常规进行BAEP检查，可及时发现病情和进行早期干预。Objective To study the changes and its clinical significance of BAEP in infantile hepatitis syndrome. Methods BEAP were measured in 50 case with infantile hepatitis syndrome. Aged from one to three months. Normal clildren of same age were studied as controis, resuhs were analysed by camparing the effect of different cause of disease and high level of bilirubin on BAEP. Results High level of bilirubin caused by different cause have effect on BAEP and there was no significant differente among different group （P 〉 0. 05） . there was significantly difference in high level of bilirubiu mainly elevated by direct bilirubin when compared with indirect bilieubin （P 〉 0. 05） . The peripheral damage （80%） was significantly more than the central damage （20%） （P 〈 0. 01 ） , The abnormality rate of BAEP in case groups was 65% , markedly higher than in control groups was 30. 4% （ P 〈0. 01 ） . Conclusion Infants with infantile hepatitis syndrome may have high abnormality rate of BAEP. It suggested that infants with infants with infantile hepatitis syndrome should have BAEP measured in order to find the abnormality as early as possible and take some treatment.

关 键 词：脑干听觉诱发电位 婴儿 肝炎综合征 

分 类 号：R725.1[医药卫生—儿科]