CD147在巧囊合并子宫腺肌症中的表达及其意义  

The Expression and clinical significance of CD147 in ovarian endometriosis and adenomyosis

作　　者：潘丽华[1] 宋丹 纪学芹[1] 

机构地区：[1]宁夏医学院附属医院,宁夏银川750004 [2]宁夏灵武市人民医院,宁夏灵武751400

出　　处：《宁夏医学杂志》2008年第9期805-806,共2页Ningxia Medical Journal

摘　　要：目的探讨CD147在卵巢巧囊合并子宫腺肌症中的表达及临床意义。方法应用免疫组化法对研究组45例子宫腺肌症合并巧囊患者的在位子宫内膜及异位子宫内膜及对照组33例正常子宫内膜进行CD147检测。结果CD147在巧囊和腺肌症的异位内膜中表达无统计学意义(P>0.05);异位内膜与在位子宫内膜相比差异有统计学意义(P<0.05);异位内膜、在位内膜与正常内膜相比差异有统计学意义(P<0.05)。结论CD147表达增强可能与子宫内膜异位症合并子宫腺肌症的发生、发展有关。Objective To study the expression and clinical significance of CD147 in ovarian endometriosis and adenomyosis. Methods Immunohistochemistry methods was employed to detect the expression of CD147 in the ectopic and eutopic endometrium of the patients （45 cases） with endometrisis and adenomyosis, and in the normal endometrium （33cases） in the control group. Results The expression of CD147 in the ectopic endometrium of ovarian endometriosis and adenomyosis was no difference （P 〉 0.05 ）. There was significant difference to ectopic endimetrium and eutopic endimetrium （ P 〈 0.05 ） and there was significant difference between the study group and control group （P 〈0.05）. Conclusion The increasing expression of CD147 may play the key role in occurrence of endometriosis and adenomyosis.

关 键 词：巧囊 子宫腺肌症 CD147 

分 类 号：R711.71[医药卫生—妇产科学]