腹腔镜下卵巢子宫内膜异位囊肿剥离术中两点注射垂体后叶素的临床观察  

The clinical value of hypophysin injection into the cornua uterus and mesosalpinx during laparoscopic stripping of ovarian endometrioma

作　　者：陈淑琴[1] 刘克玄[2] 张成美[3] 姚书忠[1] 

机构地区：[1]中山大学附属第一医院妇产科,广州510080 [2]中山大学附属第一医院麻醉科,广州510080 [3]中山大学附属第一医院体检中心,广州510080

出　　处：《中国医师进修杂志》2008年第9期19-21,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的探讨两点注射垂体后叶素在腹腔镜下卵巢子宫内膜异位囊肿剥离术中的安全性和可行性。方法将86例行腹腔镜下卵巢子宫内膜异位囊肿剥离术患者分为研究组（术中在患侧宫角和输卵管系膜无血管区注射垂体后叶素）42例和对照组（未使用垂体后叶素）44例，比较两组患者的手术时间、术中出血量、术后最高体温、术后住院天数及复发率等。结果研究组和对照组的手术时间分别为（51．24±22．58）min和（67．02±25．14）min，术中出血量分别为（42．16±26．10）ml和（68．23±28．21）ml，差异均有统计学意义（P〈0．01）；研究组和对照组的复发率分别为4．76％和11．36％，但差异无统计学意义（P〉0．05）。两组术后最高体温和术后住院天数比较差异均无统计学意义（P〉0．05）。结论腹腔镜下卵巢子宫内膜异位囊肿剥离术中应用垂体后叶素在患侧宫角及输卵管系膜无血管区注射，能减少术中出血量，缩短手术时间，并有降低复发率的可能，是一种安全、可靠、价廉、方便的方法，值得推广。Objective To evaluate the safety and the feasibility of hypophysin injection for hemostasis during laparoscopic stripping of ovarian endometrioma. Methods Retrospective analysis of 86 cases with ovarian endometrioma. Forty-two patients with prophylactic dilute hypophysin injection into cornua uterus and mesosalpinx（study group）, and 44 patients without vasopressin（control group）. The operarive time, intraoperative blood loss, the highest postoperative temperature, postoperative stay and the rate of recurrence were compared. Results The operative time in the study group and the control group were （51.24 ± 22.58）min and （67.02 ± 25.14）min, the intraoperative blood loss were （42.16 ± 26.10）ml and （68.23 ± 28.21 ）ml, respectively. There was significantly different between two groups （P 〈 0.01 ）. The rates of recurrence in the study group and the control group were 4.76% and 11.36%, respectively. But it was no significantly different between two groups（P 〉 0.05）. Both the highest postoperative temperature and postoperative stay was no difference between two groups（P 〉 0.05 ）. Conclusions Hypophysin can reduce the operative time and intraoperative blood loss during laparoscopic stripping of ovarian endometrioma, and it is possible to reduce the rate of recurrence. It is a safe, feasible, cheap and convenient method, and worth using in clinic.

关 键 词：腹腔镜 子宫内膜异位症 垂体激素类 后叶 

分 类 号：R713[医药卫生—妇产科学]