糖尿病伴贫血对糖基化血红蛋白测量的影响  

Influence of anemia on determination of glycosylated hemoglobin

作　　者：蔡明江[1] 成杰[2] 李生荣[3] 玛依努尔[1] 严利君[1] 古米娜[1] 张忆[1] 党守新[4] 

机构地区：[1]武警新疆总队医院内分泌科,新疆乌鲁木齐830091 [2]武警新疆总队医院药剂科,新疆乌鲁木齐830091 [3]武警新疆总队医院影像中心,新疆乌鲁木齐830091 [4]武警新疆总队医院康复理疗中心,新疆乌鲁木齐830091

出　　处：《海南医学院学报》2008年第5期508-509,512,共3页Journal of Hainan Medical University

摘　　要：目的:探讨糖尿病伴贫血患者在测定糖基化血红蛋白时,血红蛋白含量对糖基化血红蛋白测定的影响。方法:回顾性分析126例糖尿病伴贫血患者与132例糖尿病不伴贫血患者,糖基化血红蛋白测量的差异,用果糖胺与2周空腹血糖平均值做平行对照。结果:在相似果糖胺与空腹血糖平均值时,糖尿病伴有贫血的患者糖基化血红蛋白显著低于糖尿病不伴有贫血的患者(P<0.001)。结论:糖尿病伴贫血时血红蛋白浓度对糖基化血红蛋白测定有一定影响,临床对此结果应加以综合处理后进行评价。Objective： To determine the influence of hemoglobin contents on the determination of glycosylated hemoglobin of diabetic patients with anemia. Methods： The differences of determination of glycosylated hemoglobin were analyzed between 126 diabetic patients with anemia and 132 diabetic patients without anemia by review, while fructosamine and the average fasting blood glucoses in two weeks were applied for paralleled control. Results： Under similar levels of fructosamine and average fasting blood glucoses, the determination of glycosylated hemoglobin in diabetic patients with anemia was significant lower than that in diabetic patients without anemia（ P 〈 0.05）. Conclusion： Hemoglobin contents has some impact on the determination of glycosylated hemoglobin in diabetic patients; thus integrated overall evaluation should be done for such condition in clinic.

关 键 词：贫血 糖尿病 糖基化 血红蛋白 

分 类 号：R587.2[医药卫生—内分泌]