自体骨髓移植治疗糖尿病性动脉硬化闭塞症28例  

Treatment of diabetic arterial sclerosis and obstruction with autogenous bone marrow transplantation in 28 cases

作　　者：李斌[1] 辛明霞[1] 孙爱春[1] 

机构地区：[1]大连大学附属新华医院血管外科,辽宁省大连市116021

出　　处：《中国组织工程研究与临床康复》2008年第40期7921-7923,共3页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：为观察自体骨髓移植对糖尿病性下肢动脉硬化闭塞症血液循环的影响,对2003-06/2006-06本院收治的28例糖尿病性下肢动脉硬化闭塞症患者进行自体骨髓移植,观察移植前和移植后30d患肢踝肱指数、多普勒血流的变化。结果显示:自体骨髓移植后30d患者患肢踝肱指数、多普勒血流较移植前显著增加(P<0.01),皮肤温度升高,下肢疼痛好转的有效率为64.3%,间歇性跛行好转的有效率为39.3%,但与移植前比较差异无统计学意义。To study the benefits of autogenous bone marrow transplantation on the blood circulation of lower-extremity with diabetic arterial sclerosis and obstruction. A total of 28 patients of diabetic arterial sclerosis and obstruction treated with autogenous bone marrow transplantation, were recruited in this study from June 2003 to June 2006. Ankle-brachium index and Doppler alterations were observed before operation and 30 days after operation. Results showed that, the ankle-brachium index and circulation state of Doppler had significantly increased at 30 days after operation compared to before operation （P 〈 0.01）. Skin temperature of lower extremity also increased, and 64.3% cases had lower-extremity pain improvement, 39.3% cases had intermittent claudication improvements. There was no significant difference in comparison to before operation.

关 键 词：自体骨髓移植 动脉硬化闭塞症 糖尿病 

分 类 号：R457.7[医药卫生—治疗学]